Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 3521190..3521986 Replicon chromosome
Accession NZ_CP034105
Organism Proteus sp. GOKU

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EHE21_RS16100 Protein ID WP_194951237.1
Coordinates 3521190..3521720 (-) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EHE21_RS16105 Protein ID WP_194951238.1
Coordinates 3521717..3521986 (-) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHE21_RS16080 3516414..3517196 - 783 WP_194951233.1 TatD family hydrolase -
EHE21_RS16085 3517189..3518253 - 1065 WP_194951234.1 patatin-like phospholipase family protein -
EHE21_RS16090 3518383..3518727 - 345 WP_194951235.1 BON domain-containing protein -
EHE21_RS16095 3519332..3520921 - 1590 WP_194951236.1 peptide chain release factor 3 -
EHE21_RS16100 3521190..3521720 - 531 WP_194951237.1 GNAT family N-acetyltransferase Toxin
EHE21_RS16105 3521717..3521986 - 270 WP_194951238.1 DUF1778 domain-containing protein Antitoxin
EHE21_RS16110 3522602..3523048 - 447 WP_023582914.1 ribosomal protein S18-alanine N-acetyltransferase -
EHE21_RS16115 3523017..3523427 - 411 WP_023582915.1 DNA polymerase III subunit psi -
EHE21_RS16120 3523557..3524573 + 1017 WP_088494568.1 16S rRNA (guanine(1207)-N(2))-methyltransferase RsmC -
EHE21_RS16125 3524691..3525116 - 426 WP_194951239.1 hypothetical protein -
EHE21_RS16140 3525570..3525833 - 264 WP_194951240.1 DUF1435 family protein -
EHE21_RS16145 3526039..3526587 - 549 WP_194951241.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(5-81)


Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 20102.63 Da        Isoelectric Point: 9.5642

>T115242 WP_194951237.1 NZ_CP034105:c3521720-3521190 [Proteus sp. GOKU]
VSIGKEFEELCKLKHDRTSFDCGEVELNTFLQTQAIKHMQAGISRTMVLPSKQLLDNQKYSICAFYSITPSAIHRETLPT
SLAKKLPRYPIPVFLLAQLAVHKDFHGVGLGKISLVRALHYLWKVNTYMRAYAVVVDCLTDASKSFYAKFGFDVLCEHNG
RVRMFLPMKTIKQLFE

Download         Length: 531 bp

>T115242 NZ_CP034105:c3521720-3521190 [Proteus sp. GOKU]
GTGAGTATAGGCAAAGAGTTTGAAGAATTATGTAAGCTAAAACATGATAGGACGTCGTTTGATTGTGGGGAAGTGGAGCT
TAATACATTTCTTCAAACCCAAGCAATTAAGCATATGCAAGCTGGGATAAGCCGGACAATGGTTTTACCCAGCAAACAGT
TGTTGGATAATCAAAAATACTCGATATGTGCATTTTACAGCATAACGCCTAGTGCTATACATCGAGAAACATTACCAACA
AGTTTAGCCAAAAAGCTCCCTCGTTATCCTATACCTGTTTTTTTACTTGCTCAGTTAGCTGTGCATAAAGATTTTCATGG
CGTTGGTTTGGGGAAAATAAGCCTTGTTCGTGCGCTTCATTATTTGTGGAAGGTAAATACCTATATGAGAGCGTATGCAG
TCGTTGTTGATTGCTTAACTGATGCCTCAAAATCATTTTATGCAAAGTTTGGCTTTGATGTTCTTTGTGAGCATAATGGG
CGAGTTAGAATGTTTCTTCCGATGAAAACGATAAAACAGCTTTTTGAATAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9844.29 Da        Isoelectric Point: 4.6286

>AT115242 WP_194951238.1 NZ_CP034105:c3521986-3521717 [Proteus sp. GOKU]
MATTRLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDENATQVILQHESIEVKNDIFDEFLTACDNAKAPNQALIDAV
QLANKSGIK

Download         Length: 270 bp

>AT115242 NZ_CP034105:c3521986-3521717 [Proteus sp. GOKU]
ATGGCAACAACACGTCTTGATATTCGGCTTGACGAAGAGATAAAAGCAAAAGCTGAAAAAGCATCAGCGTTGTTAGGGCT
TAAGAGTTTAACGGAGTATGTTGTTAGGTTAATGGATGAAAATGCAACACAGGTCATTTTGCAACACGAAAGTATTGAAG
TTAAAAATGATATTTTTGATGAGTTTCTAACAGCTTGTGATAATGCTAAAGCCCCTAACCAAGCACTTATTGATGCAGTC
CAACTTGCAAATAAAAGTGGTATTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References