Detailed information of TA system
Overview
TA module
Type | II | Classification (family/domain) | tacAT/GNAT-DUF1778 |
Location | 2510693..2511438 | Replicon | chromosome |
Accession | NZ_CP034105 | ||
Organism | Proteus sp. GOKU |
Toxin (Protein)
Gene name | tacT | Uniprot ID | - |
Locus tag | EHE21_RS11715 | Protein ID | WP_194950769.1 |
Coordinates | 2510947..2511438 (+) | Length | 164 a.a. |
Antitoxin (Protein)
Gene name | tacA | Uniprot ID | - |
Locus tag | EHE21_RS11710 | Protein ID | WP_075673024.1 |
Coordinates | 2510693..2510959 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EHE21_RS11675 | 2506354..2506836 | + | 483 | WP_006533151.1 | flagellar basal body-associated protein FliL | - |
EHE21_RS11680 | 2506842..2507873 | + | 1032 | WP_023581831.1 | flagellar motor switch protein FliM | - |
EHE21_RS11685 | 2507866..2508276 | + | 411 | WP_023581830.1 | flagellar motor switch protein FliN | - |
EHE21_RS11690 | 2508280..2508726 | + | 447 | WP_023581829.1 | flagellar biosynthetic protein FliO | - |
EHE21_RS11695 | 2508783..2509496 | + | 714 | WP_171455369.1 | flagellar type III secretion system pore protein FliP | - |
EHE21_RS11700 | 2509512..2509781 | + | 270 | WP_069367481.1 | flagellar biosynthesis protein FliQ | - |
EHE21_RS11705 | 2509787..2510569 | + | 783 | WP_088495227.1 | flagellar type III secretion system protein FliR | - |
EHE21_RS11710 | 2510693..2510959 | + | 267 | WP_075673024.1 | DUF1778 domain-containing protein | Antitoxin |
EHE21_RS11715 | 2510947..2511438 | + | 492 | WP_194950769.1 | GNAT family N-acetyltransferase | Toxin |
EHE21_RS11720 | 2511523..2512467 | - | 945 | WP_194950770.1 | flagellar hook-associated protein FlgL | - |
EHE21_RS11725 | 2512499..2514142 | - | 1644 | WP_194950771.1 | flagellar hook-associated protein FlgK | - |
EHE21_RS11730 | 2514260..2515246 | - | 987 | WP_194950772.1 | flagellar assembly peptidoglycan hydrolase FlgJ | - |
EHE21_RS11735 | 2515246..2516352 | - | 1107 | WP_194950773.1 | flagellar basal body P-ring protein FlgI | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 164 a.a. Molecular weight: 18225.13 Da Isoelectric Point: 10.3494
>T115240 WP_194950769.1 NZ_CP034105:2510947-2511438 [Proteus sp. GOKU]
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAISHIRRNM
PDPIPVIILARLAVDKTFHGRGLGADLLRDAVLRCHHVAENIGVRAIMVHALTESAKHFYLHHGFKASSTQEKILFLALK
KKI
MGKVTAPEPLSNSHEVADFYSSENVLDNWIKQRGLKNQFLGASRTFVVCEKNKKRVVGYYSLATGSVNHTEAISHIRRNM
PDPIPVIILARLAVDKTFHGRGLGADLLRDAVLRCHHVAENIGVRAIMVHALTESAKHFYLHHGFKASSTQEKILFLALK
KKI
Download Length: 492 bp
>T115240 NZ_CP034105:2510947-2511438 [Proteus sp. GOKU]
ATGGGAAAAGTAACAGCACCTGAGCCGTTATCAAATTCACATGAAGTGGCTGATTTTTATAGTAGTGAAAATGTATTAGA
TAACTGGATAAAACAAAGAGGTTTAAAAAACCAATTCTTAGGTGCATCACGTACATTTGTGGTCTGTGAAAAAAATAAAA
AACGTGTTGTTGGGTACTATTCTTTAGCGACAGGTAGTGTTAACCATACTGAAGCAATTAGTCATATTCGTCGTAATATG
CCAGATCCAATACCCGTGATCATTTTAGCTAGACTGGCTGTTGATAAAACTTTTCATGGAAGAGGCCTTGGTGCCGATTT
GTTAAGAGATGCTGTTTTGCGTTGTCATCATGTAGCTGAAAACATTGGTGTTAGAGCGATTATGGTTCATGCTTTAACTG
AAAGCGCAAAACATTTTTATCTTCATCATGGTTTCAAAGCTTCTTCGACTCAAGAAAAAATCTTATTCTTGGCATTAAAA
AAGAAAATATAG
ATGGGAAAAGTAACAGCACCTGAGCCGTTATCAAATTCACATGAAGTGGCTGATTTTTATAGTAGTGAAAATGTATTAGA
TAACTGGATAAAACAAAGAGGTTTAAAAAACCAATTCTTAGGTGCATCACGTACATTTGTGGTCTGTGAAAAAAATAAAA
AACGTGTTGTTGGGTACTATTCTTTAGCGACAGGTAGTGTTAACCATACTGAAGCAATTAGTCATATTCGTCGTAATATG
CCAGATCCAATACCCGTGATCATTTTAGCTAGACTGGCTGTTGATAAAACTTTTCATGGAAGAGGCCTTGGTGCCGATTT
GTTAAGAGATGCTGTTTTGCGTTGTCATCATGTAGCTGAAAACATTGGTGTTAGAGCGATTATGGTTCATGCTTTAACTG
AAAGCGCAAAACATTTTTATCTTCATCATGGTTTCAAAGCTTCTTCGACTCAAGAAAAAATCTTATTCTTGGCATTAAAA
AAGAAAATATAG
Antitoxin
Download Length: 89 a.a. Molecular weight: 10111.62 Da Isoelectric Point: 4.5256
>AT115240 WP_075673024.1 NZ_CP034105:2510693-2510959 [Proteus sp. GOKU]
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK
MKADVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK
Download Length: 267 bp
>AT115240 NZ_CP034105:2510693-2510959 [Proteus sp. GOKU]
ATGAAAGCTGACGTACAACTCAATATTCGCGCTAAAGAATCACAACGCGCACTTATTGATACTGCTGCTGAAATTCTCCA
TAAATCTCGTACTGACTTTATTCTTGAGACAGCGTGCCAAGCTGCTGAAGACGTCATTTTAGACCGTAGAACCTTTAATT
TAAATGATGCTCAATATGCGGAATTTATAGAAATTATTGATGCGCCGGTTGATATTGACCCTGCTCTTGAAAAGTTATTA
ATGAGAAAACCATTATGGGAAAAGTAA
ATGAAAGCTGACGTACAACTCAATATTCGCGCTAAAGAATCACAACGCGCACTTATTGATACTGCTGCTGAAATTCTCCA
TAAATCTCGTACTGACTTTATTCTTGAGACAGCGTGCCAAGCTGCTGAAGACGTCATTTTAGACCGTAGAACCTTTAATT
TAAATGATGCTCAATATGCGGAATTTATAGAAATTATTGATGCGCCGGTTGATATTGACCCTGCTCTTGAAAAGTTATTA
ATGAGAAAACCATTATGGGAAAAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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