Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2183149..2184038 Replicon chromosome
Accession NZ_CP034086
Organism Methylocystis rosea strain GW6

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag EHO51_RS10615 Protein ID WP_164479383.1
Coordinates 2183508..2184038 (+) Length 177 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag EHO51_RS10610 Protein ID WP_124738874.1
Coordinates 2183149..2183511 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHO51_RS10580 2178259..2178789 - 531 WP_124738868.1 lipopolysaccharide transport periplasmic protein LptA -
EHO51_RS10585 2178790..2179494 - 705 WP_124738869.1 LPS export ABC transporter periplasmic protein LptC -
EHO51_RS10590 2179560..2180174 - 615 WP_124738870.1 ribonuclease D -
EHO51_RS10595 2180340..2180540 + 201 WP_124738871.1 hypothetical protein -
EHO51_RS10600 2180692..2181855 + 1164 WP_124738872.1 AI-2E family transporter -
EHO51_RS10605 2181823..2182998 - 1176 WP_164479382.1 lytic murein transglycosylase -
EHO51_RS10610 2183149..2183511 + 363 WP_124738874.1 hypothetical protein Antitoxin
EHO51_RS10615 2183508..2184038 + 531 WP_164479383.1 RES family NAD+ phosphorylase Toxin
EHO51_RS10620 2184046..2184339 - 294 WP_124740118.1 hypothetical protein -
EHO51_RS10625 2184458..2188240 - 3783 WP_124738875.1 SEL1-like repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(16-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 177 a.a.        Molecular weight: 19133.93 Da        Isoelectric Point: 8.9091

>T115188 WP_164479383.1 NZ_CP034086:2183508-2184038 [Methylocystis rosea]
VTAKRAPTIAVARRYWRMLAPKLAHDPLSGAGAAARGGRFNPPGLSALYMSEDFATAVAEYEQDLGIRPGTLCAYEVTSE
RIADLGDIPTLEALGVDAAILKNPWKQIAFVERRAPPSWALAKRLLAQDIDGVRVPSVQASGFNLVLWRWNIEGATKVAA
LDPLRDLPADQSSWTR

Download         Length: 531 bp

>T115188 NZ_CP034086:2183508-2184038 [Methylocystis rosea]
GTGACGGCCAAGCGCGCGCCGACGATCGCCGTCGCGCGCCGCTATTGGCGGATGCTCGCGCCGAAATTGGCCCATGATCC
CTTGAGCGGCGCCGGGGCCGCCGCGCGCGGCGGGCGCTTCAATCCGCCGGGCCTATCGGCGCTCTATATGTCCGAGGACT
TCGCGACAGCGGTCGCGGAATATGAGCAGGACCTCGGCATCAGGCCGGGAACGCTCTGCGCCTATGAAGTGACAAGCGAA
CGAATAGCGGACCTCGGCGATATTCCAACGCTTGAGGCGCTCGGCGTCGATGCCGCGATATTGAAGAATCCGTGGAAACA
GATCGCCTTCGTCGAAAGGCGCGCGCCGCCGAGCTGGGCGCTCGCCAAGCGTCTGCTTGCGCAAGACATCGACGGCGTGC
GCGTCCCTTCGGTTCAGGCTTCGGGCTTCAATCTCGTCCTTTGGCGATGGAATATCGAAGGCGCGACAAAAGTCGCGGCG
CTCGATCCGCTGCGCGACCTTCCCGCCGATCAATCCTCTTGGACGCGATGA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13091.92 Da        Isoelectric Point: 6.9903

>AT115188 WP_124738874.1 NZ_CP034086:2183149-2183511 [Methylocystis rosea]
MISAFLDQVTDRRGGFISPQRVSEALHVPLSRIARLAKVHRNTLAQRPESPLVQERLGDVARIIATATELLGGEQGRAIV
WFMHQPLSGFDGRTAEELVAAGHSDAVVAHLDLLREGSYA

Download         Length: 363 bp

>AT115188 NZ_CP034086:2183149-2183511 [Methylocystis rosea]
ATGATCAGCGCCTTCCTAGACCAAGTGACCGACCGGCGGGGCGGCTTCATTTCGCCGCAGCGCGTGAGCGAGGCGCTGCA
TGTGCCTCTCTCCAGGATTGCGCGGCTCGCCAAGGTTCATCGCAATACGCTTGCCCAGCGACCGGAGTCGCCGCTGGTGC
AAGAACGCCTCGGCGACGTCGCCAGGATCATCGCCACGGCGACCGAGCTTCTCGGCGGCGAACAGGGCCGCGCCATCGTC
TGGTTCATGCATCAGCCGCTCTCTGGTTTCGATGGACGCACCGCGGAGGAGCTGGTCGCCGCCGGCCATAGCGACGCCGT
GGTGGCGCATCTCGATCTGCTGCGCGAGGGCTCCTACGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References