Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2155884..2156389 Replicon chromosome
Accession NZ_CP034086
Organism Methylocystis rosea strain GW6

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag EHO51_RS10450 Protein ID WP_124738845.1
Coordinates 2155884..2156138 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag EHO51_RS10455 Protein ID WP_124738846.1
Coordinates 2156135..2156389 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHO51_RS10420 2151230..2151838 - 609 WP_124738840.1 nicotinate-nucleotide adenylyltransferase -
EHO51_RS10425 2151879..2152193 - 315 WP_124738841.1 HigA family addiction module antidote protein -
EHO51_RS10430 2152165..2152449 - 285 WP_124738842.1 type II toxin-antitoxin system RelE/ParE family toxin -
EHO51_RS10435 2152647..2153900 - 1254 WP_124740114.1 glutamate-5-semialdehyde dehydrogenase -
EHO51_RS10440 2154065..2154796 + 732 WP_124738843.1 class I SAM-dependent methyltransferase -
EHO51_RS10445 2154977..2155879 + 903 WP_124738844.1 DMT family transporter -
EHO51_RS10450 2155884..2156138 - 255 WP_124738845.1 Txe/YoeB family addiction module toxin Toxin
EHO51_RS10455 2156135..2156389 - 255 WP_124738846.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
EHO51_RS10465 2156583..2158388 - 1806 WP_124738848.1 translation elongation factor 4 -
EHO51_RS10470 2158501..2159094 - 594 WP_124738849.1 hypothetical protein -
EHO51_RS10475 2159288..2159584 - 297 WP_124738850.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10171.72 Da        Isoelectric Point: 9.0358

>T115186 WP_124738845.1 NZ_CP034086:c2156138-2155884 [Methylocystis rosea]
MKLVFAEQAWADYLYWQGQDKKTLERINMLIKECSRTPFEGLGKPEPLRGDLRGWWSRRIDREHRLVYRVEDGALLIAQC
RYHY

Download         Length: 255 bp

>T115186 NZ_CP034086:c2156138-2155884 [Methylocystis rosea]
ATGAAGCTCGTCTTCGCCGAACAGGCTTGGGCCGATTATCTCTATTGGCAAGGCCAAGATAAAAAGACTCTCGAACGCAT
TAACATGCTCATCAAAGAGTGTAGTCGCACGCCCTTCGAAGGGCTTGGCAAGCCGGAACCCTTACGTGGCGATTTACGCG
GCTGGTGGTCACGCCGCATCGATCGGGAGCATCGCCTCGTTTATCGCGTCGAAGACGGCGCCTTGCTGATTGCTCAGTGC
CGCTATCATTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9504.70 Da        Isoelectric Point: 5.8768

>AT115186 WP_124738846.1 NZ_CP034086:c2156389-2156135 [Methylocystis rosea]
MRTTSYSDLRKNLAATLDRVTEDHEPVVITRDKGKPAAVLISLEDFASYEETSYLLQSPRNAERLRAAIQELDAGRGKER
KLVE

Download         Length: 255 bp

>AT115186 NZ_CP034086:c2156389-2156135 [Methylocystis rosea]
ATGCGCACAACCTCTTACAGCGATCTCCGCAAGAATCTCGCCGCTACGCTCGATCGCGTCACGGAAGACCATGAGCCGGT
CGTCATCACCCGCGACAAAGGCAAGCCTGCAGCCGTGCTGATCTCGCTCGAAGACTTCGCCTCCTATGAAGAGACCAGCT
ATCTGCTGCAGAGTCCGCGCAATGCAGAGCGCTTGCGCGCAGCCATCCAGGAGCTCGACGCGGGGCGTGGAAAAGAGCGC
AAGCTCGTTGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References