Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2077841..2077986 Replicon chromosome
Accession NZ_CP034082
Organism Klebsiella pneumoniae subsp. pneumoniae strain R210-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2077877..2077979 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2077841..2077986 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHV09_RS10250 2072971..2075031 + 2061 WP_004151449.1 oligopeptidase B -
EHV09_RS10255 2075035..2075694 - 660 WP_002911407.1 exodeoxyribonuclease X -
EHV09_RS10260 2075773..2076003 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EHV09_RS10265 2076116..2076490 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EHV09_RS10270 2076494..2077363 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
EHV09_RS10275 2077380..2077718 + 339 WP_002911404.1 YebY family protein -
- 2077841..2077986 - 146 - - Antitoxin
- 2077877..2077979 + 103 - - Toxin
EHV09_RS30135 2078354..2078497 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EHV09_RS10285 2078602..2079570 - 969 WP_164483505.1 VirK/YbjX family protein -
EHV09_RS10290 2079727..2080380 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EHV09_RS10295 2080377..2080568 - 192 WP_002911395.1 YebW family protein -
EHV09_RS10300 2080666..2080905 - 240 WP_002911393.1 YebV family protein -
EHV09_RS10305 2081021..2082454 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115164 NZ_CP034082:2077877-2077979 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115164 NZ_CP034082:c2077986-2077841 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References