Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 2089257..2089770 Replicon chromosome
Accession NZ_CP034078
Organism Pseudomonas syringae pv. pisi str. PP1

Toxin (Protein)


Gene name relE Uniprot ID A0A7Z6Y8M4
Locus tag N032_RS09865 Protein ID WP_003348947.1
Coordinates 2089257..2089541 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3M4E5F0
Locus tag N032_RS09870 Protein ID WP_024648170.1
Coordinates 2089531..2089770 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N032_RS09850 2085399..2087327 + 1929 WP_024648167.1 methyl-accepting chemotaxis protein -
N032_RS09855 2087361..2088293 - 933 WP_024648168.1 DMT family transporter -
N032_RS09860 2088368..2089222 + 855 WP_024648169.1 LysR family transcriptional regulator -
N032_RS09865 2089257..2089541 - 285 WP_003348947.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N032_RS09870 2089531..2089770 - 240 WP_024648170.1 CopG family ribbon-helix-helix protein Antitoxin
N032_RS09875 2089930..2090946 - 1017 WP_003423368.1 1-aminocyclopropane-1-carboxylate deaminase -
N032_RS09880 2091133..2091639 + 507 WP_003315203.1 Lrp/AsnC family transcriptional regulator -
N032_RS09885 2091786..2092694 + 909 WP_003423371.1 DUF808 domain-containing protein -
N032_RS09890 2092871..2093656 - 786 WP_003423373.1 membrane protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10602.32 Da        Isoelectric Point: 10.4249

>T115152 WP_003348947.1 NZ_CP034078:c2089541-2089257 [Pseudomonas syringae pv. pisi str. PP1]
MQVEWLKTALKNLDEEAAYIALDNPAAAAAFVKAIQSSVTQLASFPAMGREGRIAGTREWPLPDLPYLIPYRIRSGRLQV
LRIFHARRQSPPVW

Download         Length: 285 bp

>T115152 NZ_CP034078:c2089541-2089257 [Pseudomonas syringae pv. pisi str. PP1]
ATGCAGGTTGAGTGGCTCAAAACAGCACTAAAGAATCTGGATGAGGAGGCAGCGTATATCGCACTGGACAATCCAGCTGC
TGCCGCTGCTTTCGTGAAAGCCATTCAATCAAGCGTAACGCAGCTCGCGAGCTTTCCCGCCATGGGCCGGGAAGGACGGA
TTGCCGGAACCAGAGAATGGCCTCTGCCAGACCTGCCTTACCTGATTCCATATCGCATCCGTAGCGGCCGACTACAGGTT
CTACGGATTTTCCACGCCAGAAGACAATCGCCACCCGTGTGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8715.80 Da        Isoelectric Point: 4.4354

>AT115152 WP_024648170.1 NZ_CP034078:c2089770-2089531 [Pseudomonas syringae pv. pisi str. PP1]
MSTMSLRLPDEMADTLAHLAKATGRSKSFLALDALREYLTREAWQIAEIQRAIEEADAGEFASQEDVKAVMDKWSGNAG

Download         Length: 240 bp

>AT115152 NZ_CP034078:c2089770-2089531 [Pseudomonas syringae pv. pisi str. PP1]
ATGTCCACAATGTCTCTACGTCTGCCGGACGAAATGGCAGATACCCTTGCACACCTTGCAAAGGCGACCGGGCGCAGCAA
GTCATTTTTGGCCCTCGACGCGCTCCGCGAATACCTGACACGCGAGGCTTGGCAGATTGCCGAAATTCAGCGTGCCATCG
AAGAAGCCGACGCCGGCGAGTTCGCAAGCCAAGAAGACGTAAAAGCTGTCATGGACAAATGGTCAGGCAATGCAGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Z6Y8M4

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4E5F0

References