Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1998118..1998263 Replicon chromosome
Accession NZ_CP034077
Organism Klebsiella pneumoniae strain KP17-16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1998154..1998256 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1998118..1998263 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EHE18_RS09800 1993248..1995308 + 2061 WP_004151449.1 oligopeptidase B -
EHE18_RS09805 1995312..1995971 - 660 WP_020324964.1 exodeoxyribonuclease X -
EHE18_RS09810 1996050..1996280 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EHE18_RS09815 1996393..1996767 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EHE18_RS09820 1996771..1997640 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
EHE18_RS09825 1997657..1997995 + 339 WP_002911404.1 YebY family protein -
- 1998118..1998263 - 146 - - Antitoxin
- 1998154..1998256 + 103 - - Toxin
EHE18_RS26745 1998632..1998775 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EHE18_RS09835 1998880..1999848 - 969 WP_004151446.1 VirK/YbjX family protein -
EHE18_RS09840 2000005..2000658 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EHE18_RS09845 2000655..2000846 - 192 WP_002911395.1 YebW family protein -
EHE18_RS09850 2000944..2001183 - 240 WP_002911393.1 YebV family protein -
EHE18_RS09855 2001299..2002732 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115136 NZ_CP034077:1998154-1998256 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115136 NZ_CP034077:c1998263-1998118 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References