Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2285923..2286157 | Replicon | chromosome |
| Accession | NZ_CP034060 | ||
| Organism | Shigella flexneri strain FDAARGOS_535 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2286053..2286156 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2285923..2286157 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGX88_RS12995 | 2282478..2283140 | - | 663 | WP_000944271.1 | exodeoxyribonuclease X | - |
| EGX88_RS13000 | 2283164..2283820 | - | 657 | Protein_2188 | carbon-nitrogen hydrolase family protein | - |
| EGX88_RS13005 | 2283922..2284152 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| EGX88_RS13010 | 2284291..2284665 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| EGX88_RS13015 | 2284669..2285541 | + | 873 | Protein_2191 | copper homeostasis membrane protein CopD | - |
| EGX88_RS13020 | 2285554..2285895 | + | 342 | WP_000976476.1 | YebY family protein | - |
| - | 2285923..2286157 | - | 235 | - | - | Antitoxin |
| - | 2286053..2286156 | + | 104 | - | - | Toxin |
| EGX88_RS13025 | 2286288..2287364 | - | 1077 | Protein_2193 | phage integrase Arm DNA-binding domain-containing protein | - |
| EGX88_RS13030 | 2287330..2287611 | - | 282 | WP_005127484.1 | excisionase | - |
| EGX88_RS13035 | 2287728..2288576 | - | 849 | Protein_2195 | IS3-like element IS600 family transposase | - |
| EGX88_RS13040 | 2288631..2289840 | + | 1210 | Protein_2196 | IS3 family transposase | - |
| EGX88_RS13045 | 2289883..2290193 | - | 311 | Protein_2197 | transposase | - |
| EGX88_RS13050 | 2290257..2290724 | + | 468 | Protein_2198 | DNA-binding transcriptional regulator PgrR | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T115077 NZ_CP034060:2286053-2286156 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT115077 NZ_CP034060:c2286157-2285923 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
