Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 3031011..3031573 Replicon chromosome
Accession NZ_CP034058
Organism Anabaena sp. YBS01

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EH233_RS13000 Protein ID WP_011319780.1
Coordinates 3031011..3031352 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EH233_RS13005 Protein ID WP_011319779.1
Coordinates 3031349..3031573 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EH233_RS12965 3026134..3026322 + 189 WP_104009873.1 hypothetical protein -
EH233_RS12970 3026333..3026551 + 219 WP_010994726.1 DUF4327 family protein -
EH233_RS12975 3026672..3027073 - 402 WP_011317236.1 four helix bundle protein -
EH233_RS12980 3027254..3027610 - 357 Protein_2561 CBS domain-containing protein -
EH233_RS12985 3028144..3029400 - 1257 WP_041456239.1 ABC transporter substrate-binding protein -
EH233_RS12990 3029525..3029932 + 408 WP_011319782.1 hypothetical protein -
EH233_RS12995 3030205..3030978 + 774 WP_011319781.1 hypothetical protein -
EH233_RS13000 3031011..3031352 - 342 WP_011319780.1 DUF5615 family PIN-like protein Toxin
EH233_RS13005 3031349..3031573 - 225 WP_011319779.1 DUF433 domain-containing protein Antitoxin
EH233_RS13010 3031623..3032987 - 1365 WP_011319778.1 tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB -
EH233_RS13015 3033152..3034234 - 1083 WP_011319777.1 serine/threonine protein kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(4-79)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12430.35 Da        Isoelectric Point: 4.2457

>T115066 WP_011319780.1 NZ_CP034058:c3031352-3031011 [Anabaena sp. YBS01]
MTTIWIDAHLSPVIATWINNTFGITALALRDIGLRDAEDLEIFEAAKAQGVIFITKDSDFVDLVERLGEPPKIIWLTCGN
TSNARLQEILSVTLPDALRLLQAGERLVEISGV

Download         Length: 342 bp

>T115066 NZ_CP034058:c3031352-3031011 [Anabaena sp. YBS01]
ATGACAACGATTTGGATTGATGCACATCTGTCGCCGGTGATTGCTACCTGGATTAACAACACATTTGGGATTACAGCATT
GGCATTGCGTGACATTGGCTTGAGGGATGCTGAAGACCTGGAGATTTTTGAAGCAGCAAAAGCTCAAGGAGTTATCTTCA
TCACCAAAGACAGCGATTTTGTTGACTTAGTAGAACGCTTAGGAGAGCCACCAAAAATCATCTGGCTAACCTGCGGTAAT
ACATCAAATGCTCGTTTGCAAGAGATTCTGAGTGTTACACTACCGGACGCATTGAGGCTTCTACAAGCAGGCGAGAGATT
GGTAGAGATTAGCGGAGTTTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8104.53 Da        Isoelectric Point: 7.8328

>AT115066 WP_011319779.1 NZ_CP034058:c3031573-3031349 [Anabaena sp. YBS01]
MSNLLQRITVNPKQCGGRPCIRGMRIRVSDVLDLLAAGLSSEQILAEMPDLEMDDLKASLAYAARKLNHPILTA

Download         Length: 225 bp

>AT115066 NZ_CP034058:c3031573-3031349 [Anabaena sp. YBS01]
ATGTCAAACTTGTTGCAAAGAATCACAGTCAACCCTAAACAGTGTGGTGGTCGTCCCTGCATTCGTGGTATGAGAATTAG
GGTATCAGATGTACTTGATTTGTTAGCTGCGGGACTTAGCTCCGAGCAAATCTTAGCAGAAATGCCCGATTTAGAGATGG
ATGATTTGAAAGCATCACTCGCTTACGCTGCTCGTAAATTAAATCATCCCATCCTGACGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References