Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2036161..2036306 Replicon chromosome
Accession NZ_CP034039
Organism Klebsiella pneumoniae subsp. pneumoniae strain CRK0298

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2036197..2036299 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2036161..2036306 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C5X33_RS10175 2031291..2033351 + 2061 WP_004151449.1 oligopeptidase B -
C5X33_RS10180 2033355..2034014 - 660 WP_002911407.1 exodeoxyribonuclease X -
C5X33_RS10185 2034093..2034323 - 231 WP_002911406.1 DNA polymerase III subunit theta -
C5X33_RS10190 2034436..2034810 + 375 WP_004151448.1 CopC domain-containing protein YobA -
C5X33_RS10195 2034814..2035683 + 870 WP_019725445.1 copper homeostasis membrane protein CopD -
C5X33_RS10200 2035700..2036038 + 339 WP_002911404.1 YebY family protein -
- 2036161..2036306 - 146 - - Antitoxin
- 2036197..2036299 + 103 - - Toxin
C5X33_RS29590 2036674..2036817 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
C5X33_RS10210 2036922..2037890 - 969 WP_004151446.1 VirK/YbjX family protein -
C5X33_RS10215 2038047..2038700 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
C5X33_RS10220 2038697..2038888 - 192 WP_002911395.1 YebW family protein -
C5X33_RS10225 2038986..2039225 - 240 WP_002911393.1 YebV family protein -
C5X33_RS10230 2039341..2040774 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T115025 NZ_CP034039:2036197-2036299 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT115025 NZ_CP034039:c2036306-2036161 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References