Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 543358..544018 Replicon chromosome
Accession NZ_CP034035
Organism Brenneria rubrifaciens strain 6D370

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag EH207_RS02635 Protein ID WP_137712609.1
Coordinates 543605..544018 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag EH207_RS02630 Protein ID WP_137712608.1
Coordinates 543358..543624 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EH207_RS02610 539070..540377 + 1308 WP_137712604.1 ABC transporter substrate-binding protein -
EH207_RS02615 540560..541168 - 609 WP_137712605.1 HD domain-containing protein -
EH207_RS02620 541425..542072 + 648 WP_137712606.1 hemolysin III family protein -
EH207_RS02625 542132..543118 - 987 WP_137712607.1 tRNA-modifying protein YgfZ -
EH207_RS02630 543358..543624 + 267 WP_137712608.1 FAD assembly factor SdhE Antitoxin
EH207_RS02635 543605..544018 + 414 WP_137712609.1 protein YgfX Toxin
EH207_RS02640 544093..545040 + 948 WP_137712610.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
EH207_RS02645 545048..545566 - 519 WP_137712611.1 flavodoxin FldB -
EH207_RS02650 545682..547007 - 1326 WP_137712612.1 MHS family MFS transporter -
EH207_RS02655 547367..548266 + 900 WP_137715236.1 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-78)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16125.90 Da        Isoelectric Point: 11.4239

>T114983 WP_137712609.1 NZ_CP034035:543605-544018 [Brenneria rubrifaciens]
VAQWQCDLRVSWRMQLFSLIVHGLLVLLILLAPWPDGYAVVWLGLVTLVVFGFIRSQRNIKSRQGEISLRSETNLRWQQQ
EWQIVKRPWVLNNGILLSLKASDGKARQRLWLASDSMGDDEWRHLRQLLLQPKSWVR

Download         Length: 414 bp

>T114983 NZ_CP034035:543605-544018 [Brenneria rubrifaciens]
GTGGCCCAGTGGCAATGTGATCTGCGTGTTTCCTGGCGCATGCAGCTTTTTTCACTGATCGTGCATGGGCTATTGGTGTT
GCTGATCCTGCTGGCTCCCTGGCCGGATGGTTACGCCGTGGTGTGGCTGGGACTGGTTACGCTGGTGGTGTTCGGCTTTA
TTCGTAGTCAACGAAATATTAAATCCCGGCAAGGGGAAATTTCACTACGCAGCGAGACGAATCTGCGCTGGCAGCAACAG
GAATGGCAAATCGTCAAACGTCCCTGGGTGTTGAATAATGGCATTTTGCTCTCTTTGAAAGCGTCCGATGGGAAAGCGCG
GCAGAGGCTGTGGCTGGCGTCCGACAGCATGGGAGACGACGAATGGCGTCATTTGCGCCAGTTGCTGTTGCAGCCTAAAA
GCTGGGTAAGATAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10539.07 Da        Isoelectric Point: 5.6177

>AT114983 WP_137712608.1 NZ_CP034035:543358-543624 [Brenneria rubrifaciens]
MEIDNKSRIHWACRRGMRELDLSIMPFFEHEYDALSDDDKRTFVRLLQCDDPDLFNWLMNHGEPQDQALKRMVSLIQMRN
KDRGPVAM

Download         Length: 267 bp

>AT114983 NZ_CP034035:543358-543624 [Brenneria rubrifaciens]
ATGGAAATCGATAATAAGTCTCGGATTCACTGGGCATGTCGCCGTGGCATGCGTGAGCTGGATCTTTCTATCATGCCTTT
TTTTGAGCATGAGTATGACGCATTGAGCGATGATGACAAACGAACGTTTGTGCGTCTGTTGCAATGTGACGATCCCGATC
TGTTTAACTGGCTGATGAATCACGGCGAACCGCAAGATCAGGCGTTAAAGCGCATGGTTTCCCTTATCCAGATGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References