Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 4580119..4581074 Replicon chromosome
Accession NZ_CP033972
Organism Gordonia insulae strain MMS17-SY073

Toxin (Protein)


Gene name pezT Uniprot ID -
Locus tag D7316_RS20895 Protein ID WP_124709959.1
Coordinates 4580119..4580691 (-) Length 191 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID -
Locus tag D7316_RS20900 Protein ID WP_124709960.1
Coordinates 4580688..4581074 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7316_RS20880 4575748..4576602 - 855 WP_197718279.1 DUF2236 domain-containing protein -
D7316_RS20885 4576728..4579055 - 2328 WP_124709957.1 MFS transporter -
D7316_RS20890 4579228..4580058 + 831 WP_124709958.1 SDR family NAD(P)-dependent oxidoreductase -
D7316_RS20895 4580119..4580691 - 573 WP_124709959.1 zeta toxin family protein Toxin
D7316_RS20900 4580688..4581074 - 387 WP_124709960.1 hypothetical protein Antitoxin
D7316_RS20905 4581157..4581981 - 825 WP_124709961.1 SDR family NAD(P)-dependent oxidoreductase -
D7316_RS20910 4582281..4583294 - 1014 WP_124709962.1 ferritin-like domain-containing protein -
D7316_RS20915 4583499..4583966 + 468 WP_124709963.1 MarR family transcriptional regulator -
D7316_RS20920 4583963..4585201 + 1239 WP_124709964.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(5-134)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-106)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21000.99 Da        Isoelectric Point: 8.4813

>T114759 WP_124709959.1 NZ_CP033972:c4580691-4580119 [Gordonia insulae]
VRRLDLVIGPNGAGKSTFVEYTLAPLLPGSVFVNADLIARRRWPEEAEARSYDAARIAAATRERLIDDGRSFIAETVFSH
ESKLELIDRAHAAGYFVVLHVLLVPEALAVLRVAYRQSAGGHSVPEHKIRARYRRLWPLAADAVHRTDEATVYNTALDRA
PTIVAEFTQGVLVGAARWPEWAPGELVRLG

Download         Length: 573 bp

>T114759 NZ_CP033972:c4580691-4580119 [Gordonia insulae]
GTGAGGCGCCTGGATCTGGTGATCGGCCCGAACGGCGCCGGAAAGTCGACGTTCGTCGAGTACACCCTCGCTCCCCTGTT
GCCGGGGAGCGTCTTCGTCAACGCGGACCTCATCGCGCGCCGACGCTGGCCCGAGGAGGCCGAGGCACGCTCCTACGATG
CCGCGCGAATCGCCGCGGCGACGCGGGAACGGTTGATCGACGACGGGCGCTCGTTCATCGCCGAGACCGTGTTCTCGCAT
GAATCAAAGCTCGAGCTGATCGACCGAGCACATGCAGCCGGGTACTTTGTCGTGCTCCACGTCCTGCTCGTCCCCGAGGC
TCTTGCGGTCCTGCGAGTCGCCTACCGACAATCGGCGGGCGGGCATTCGGTGCCAGAGCACAAGATCCGCGCCCGCTACC
GGCGGCTCTGGCCGCTCGCCGCCGATGCCGTTCACCGGACCGACGAGGCGACGGTCTACAACACCGCGCTCGACCGGGCT
CCCACCATCGTCGCCGAGTTCACCCAAGGGGTGCTCGTCGGAGCCGCCAGGTGGCCCGAGTGGGCGCCTGGCGAACTCGT
GAGGCTCGGATGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 13935.36 Da        Isoelectric Point: 5.2566

>AT114759 WP_124709960.1 NZ_CP033972:c4581074-4580688 [Gordonia insulae]
MTRAADKVTRVDADLVDSAIAEGRRQQRTGRQQLEYWARVGRALTTHESASLRRVQAALSGAIPTTDLGGDEGRAFNAQI
RARVSEDLATADYRRELSASGVTTVSLDEAGRIVEHLPDGTTRVLDDE

Download         Length: 387 bp

>AT114759 NZ_CP033972:c4581074-4580688 [Gordonia insulae]
ATGACCAGAGCCGCGGACAAGGTCACCCGCGTCGACGCCGACCTCGTCGACAGCGCGATCGCCGAAGGCCGTCGTCAACA
GCGAACCGGACGACAGCAACTCGAGTACTGGGCGCGCGTCGGCCGCGCACTCACCACCCACGAGTCCGCGTCACTGAGGC
GCGTCCAGGCCGCGCTGTCGGGAGCCATACCGACAACCGACCTCGGGGGCGACGAAGGCCGCGCGTTCAACGCCCAGATC
CGCGCCCGGGTGAGCGAGGATCTGGCCACGGCGGACTACCGACGCGAACTCTCCGCGAGTGGAGTCACCACCGTGTCGCT
CGATGAGGCCGGCCGGATCGTCGAACACCTGCCGGACGGGACCACCCGAGTCCTCGACGACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References