114756

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1231986..1232602 Replicon chromosome
Accession NZ_CP033972
Organism Gordonia insulae strain MMS17-SY073

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D7316_RS05615 Protein ID WP_124707404.1
Coordinates 1231986..1232393 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D7316_RS05620 Protein ID WP_164473731.1
Coordinates 1232390..1232602 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D7316_RS05590 1227705..1228961 + 1257 WP_124707401.1 amidohydrolase family protein -
D7316_RS05595 1228954..1229592 + 639 WP_124707402.1 DUF1097 domain-containing protein -
D7316_RS05600 1229589..1229957 + 369 WP_197718191.1 oxalurate catabolism protein HpxZ -
D7316_RS05605 1230077..1231291 + 1215 WP_124711140.1 glutamyl-tRNA amidotransferase -
D7316_RS05610 1231361..1231942 + 582 WP_124707403.1 dihydrofolate reductase family protein -
D7316_RS05615 1231986..1232393 - 408 WP_124707404.1 PIN domain-containing protein Toxin
D7316_RS05620 1232390..1232602 - 213 WP_164473731.1 ribbon-helix-helix domain-containing protein Antitoxin
D7316_RS05625 1232723..1234276 - 1554 WP_124707405.1 YdiU family protein -
D7316_RS05630 1234611..1235096 + 486 WP_124711142.1 hypothetical protein -
D7316_RS05635 1235553..1237244 + 1692 WP_164473732.1 AAA family ATPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-118)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-39)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14646.64 Da        Isoelectric Point: 4.3736

>T114756 WP_124707404.1 NZ_CP033972:c1232393-1231986 [Gordonia insulae]
VIVDTSALLAYFDAAEPQHEAVAVLIDAADEPLVVSPYIVAELDYLVLTRHGSHIERLVLDELTSGAWELATMSRERLAT
AAEIVRQYSDVPVGVADASNIVLADAYRTRTVATLDHRHFTVLRLGDGSAPLIIP

Download         Length: 408 bp

>T114756 NZ_CP033972:c1232393-1231986 [Gordonia insulae]
GTGATCGTCGACACCAGCGCACTGCTGGCGTATTTCGACGCTGCTGAACCGCAGCATGAAGCTGTCGCGGTGTTGATCGA
CGCAGCAGATGAGCCCTTGGTCGTATCACCGTACATCGTGGCCGAACTCGACTATCTCGTGCTGACTCGCCATGGCTCGC
ACATCGAGCGCCTCGTGCTCGATGAACTGACTTCGGGCGCTTGGGAACTCGCCACCATGTCGCGTGAGCGGTTGGCGACC
GCTGCGGAGATCGTTCGACAGTATTCCGACGTGCCCGTCGGTGTGGCCGACGCGTCGAACATCGTCTTGGCCGACGCCTA
TCGGACCAGGACGGTTGCGACCCTCGATCATCGCCACTTCACTGTCCTCCGTCTCGGCGACGGTTCGGCCCCATTGATCA
TTCCGTGA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7775.91 Da        Isoelectric Point: 8.6860

>AT114756 WP_164473731.1 NZ_CP033972:c1232602-1232390 [Gordonia insulae]
MAKTTLYLPDDLKRAIELEARRRSLPEAEIVRQALRKALSGNTPRPRGALFSGNEPIADRVDVLLDGFGE

Download         Length: 213 bp

>AT114756 NZ_CP033972:c1232602-1232390 [Gordonia insulae]
ATGGCCAAAACTACGCTTTACCTCCCGGATGACTTGAAGCGGGCCATCGAACTCGAAGCGCGCCGGCGATCGCTTCCGGA
GGCCGAGATTGTCCGGCAGGCTTTGCGTAAAGCTCTGAGCGGCAATACGCCCCGACCTCGGGGCGCATTGTTCTCGGGCA
ACGAACCCATCGCTGATCGTGTTGACGTGCTACTTGACGGCTTCGGCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References