114747

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 5411726..5412297 Replicon chromosome
Accession NZ_CP033966
Organism Pigmentiphaga sp. H8

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EGT29_RS25540 Protein ID WP_202865569.1
Coordinates 5412010..5412297 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EGT29_RS25535 Protein ID WP_124691626.1
Coordinates 5411726..5412013 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGT29_RS25510 5407953..5408768 + 816 WP_124691621.1 SDR family oxidoreductase -
EGT29_RS25515 5408777..5409148 + 372 WP_124691622.1 dihydroneopterin aldolase -
EGT29_RS25520 5409150..5410124 + 975 WP_124691623.1 tRNA 2-thiocytidine(32) synthetase TtcA -
EGT29_RS25525 5410121..5410876 + 756 WP_124691624.1 ABC transporter ATP-binding protein -
EGT29_RS25530 5410873..5411640 + 768 WP_124691625.1 ABC transporter permease -
EGT29_RS25535 5411726..5412013 + 288 WP_124691626.1 hypothetical protein Antitoxin
EGT29_RS25540 5412010..5412297 + 288 WP_202865569.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EGT29_RS25545 5412303..5413295 + 993 WP_124691627.1 ABC transporter substrate-binding protein -
EGT29_RS25550 5413325..5414221 + 897 WP_124691628.1 LysR family transcriptional regulator -
EGT29_RS25555 5414218..5415195 - 978 WP_124691629.1 tripartite tricarboxylate transporter substrate binding protein -
EGT29_RS25560 5415210..5415800 - 591 WP_124691630.1 2-hydroxychromene-2-carboxylate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11052.61 Da        Isoelectric Point: 5.5803

>T114747 WP_202865569.1 NZ_CP033966:5412010-5412297 [Pigmentiphaga sp. H8]
MIQLYWTFEAIGDRESIYDYIETDNPVAALALDELFEEKSGRLIDHPDMGRPGRVAGTRELVVHRHYVLVYDMTGEKIRV
LRVLHAARQWPPSKE

Download         Length: 288 bp

>T114747 NZ_CP033966:5412010-5412297 [Pigmentiphaga sp. H8]
ATGATCCAACTGTATTGGACGTTCGAGGCCATTGGCGACCGTGAATCGATCTATGACTACATCGAGACCGACAACCCTGT
CGCCGCACTCGCCCTCGACGAACTGTTTGAAGAAAAATCCGGCCGCCTGATCGACCACCCGGACATGGGCCGGCCTGGCC
GTGTCGCCGGTACCCGGGAACTCGTCGTACACAGGCACTATGTGCTGGTTTATGACATGACCGGCGAGAAAATACGTGTA
CTGCGTGTACTGCACGCAGCCCGGCAATGGCCACCATCCAAGGAGTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10815.99 Da        Isoelectric Point: 10.4219

>AT114747 WP_124691626.1 NZ_CP033966:5411726-5412013 [Pigmentiphaga sp. H8]
MSEATFTFRVDESLKTAFATAAKARDRTGAQLLRDFMREFVQQQHEAAEHDTWFRREVKAGQDSANGGRLAPAAEVETRF
AARRAATRRRLEQSE

Download         Length: 288 bp

>AT114747 NZ_CP033966:5411726-5412013 [Pigmentiphaga sp. H8]
ATGAGCGAGGCAACCTTTACATTCAGGGTCGATGAGTCGCTGAAGACCGCTTTCGCCACCGCGGCCAAGGCTCGCGACCG
GACCGGCGCCCAACTTCTACGCGACTTCATGCGCGAATTCGTGCAGCAACAACATGAAGCGGCCGAACATGACACCTGGT
TCCGCCGCGAAGTGAAAGCCGGGCAGGACTCCGCGAATGGCGGCCGTCTGGCACCGGCCGCCGAGGTCGAAACCCGATTC
GCAGCCCGTCGGGCTGCCACGCGCCGCCGGCTTGAACAGTCAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References