Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 3471571..3472239 | Replicon | chromosome |
Accession | NZ_CP033966 | ||
Organism | Pigmentiphaga sp. H8 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | - |
Locus tag | EGT29_RS16410 | Protein ID | WP_124689986.1 |
Coordinates | 3472063..3472239 (-) | Length | 59 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | - |
Locus tag | EGT29_RS16405 | Protein ID | WP_124689985.1 |
Coordinates | 3471571..3471984 (-) | Length | 138 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EGT29_RS16380 | 3467377..3467919 | + | 543 | WP_124692392.1 | biofilm regulation protein kinase SiaB | - |
EGT29_RS16385 | 3467938..3468315 | + | 378 | WP_124689982.1 | biofilm regulation phosphoprotein SiaC | - |
EGT29_RS16390 | 3468327..3469115 | + | 789 | WP_124689983.1 | biofilm regulation diguanylate cyclase SiaD | - |
EGT29_RS16395 | 3469253..3471274 | + | 2022 | WP_124689984.1 | FUSC family protein | - |
EGT29_RS16405 | 3471571..3471984 | - | 414 | WP_124689985.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
EGT29_RS16410 | 3472063..3472239 | - | 177 | WP_124689986.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
EGT29_RS16420 | 3472609..3473544 | - | 936 | WP_124689987.1 | 3-keto-5-aminohexanoate cleavage protein | - |
EGT29_RS16425 | 3473566..3474435 | - | 870 | WP_124689988.1 | fumarylacetoacetate hydrolase family protein | - |
EGT29_RS16430 | 3474447..3475382 | - | 936 | WP_124689989.1 | VOC family protein | - |
EGT29_RS16435 | 3475392..3476372 | - | 981 | WP_124689990.1 | tripartite tricarboxylate transporter substrate binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 59 a.a. Molecular weight: 6535.57 Da Isoelectric Point: 10.9585
>T114745 WP_124689986.1 NZ_CP033966:c3472239-3472063 [Pigmentiphaga sp. H8]
VKVNEFRRWLAAQGATFKEGAGHTKVYYQGKQTTLPRHPSQELGEGLRKAILKQLGIK
VKVNEFRRWLAAQGATFKEGAGHTKVYYQGKQTTLPRHPSQELGEGLRKAILKQLGIK
Download Length: 177 bp
>T114745 NZ_CP033966:c3472239-3472063 [Pigmentiphaga sp. H8]
GTGAAAGTTAACGAGTTCCGGCGATGGTTAGCTGCCCAGGGCGCCACATTCAAGGAAGGCGCCGGTCACACAAAGGTGTA
CTACCAGGGCAAGCAGACCACTCTGCCAAGGCACCCAAGCCAGGAGCTTGGGGAAGGGCTGAGAAAGGCGATTCTCAAGC
AACTGGGGATCAAGTAA
GTGAAAGTTAACGAGTTCCGGCGATGGTTAGCTGCCCAGGGCGCCACATTCAAGGAAGGCGCCGGTCACACAAAGGTGTA
CTACCAGGGCAAGCAGACCACTCTGCCAAGGCACCCAAGCCAGGAGCTTGGGGAAGGGCTGAGAAAGGCGATTCTCAAGC
AACTGGGGATCAAGTAA
Antitoxin
Download Length: 138 a.a. Molecular weight: 15080.36 Da Isoelectric Point: 5.0019
>AT114745 WP_124689985.1 NZ_CP033966:c3471984-3471571 [Pigmentiphaga sp. H8]
MRYAARIEPDGNVFMVSFRDIPEALTAADTREEAEAAAADALRTAMDFYFEDRRAVPLPSKAQAGEVLVELPASLWAKVL
LLNEMVRQDVAPVELARRLGTRKQEVTRIMDLGHATKIDTIAAALASLGRELSLSVR
MRYAARIEPDGNVFMVSFRDIPEALTAADTREEAEAAAADALRTAMDFYFEDRRAVPLPSKAQAGEVLVELPASLWAKVL
LLNEMVRQDVAPVELARRLGTRKQEVTRIMDLGHATKIDTIAAALASLGRELSLSVR
Download Length: 414 bp
>AT114745 NZ_CP033966:c3471984-3471571 [Pigmentiphaga sp. H8]
ATGCGCTACGCCGCTCGAATCGAACCGGATGGCAACGTTTTCATGGTGTCGTTCCGCGACATCCCCGAAGCTCTGACGGC
TGCGGATACCCGCGAGGAAGCCGAGGCCGCAGCGGCCGATGCATTGCGCACGGCCATGGACTTCTATTTCGAGGATCGAC
GGGCCGTACCCCTGCCGTCCAAGGCCCAGGCCGGTGAGGTCCTGGTTGAACTACCTGCCAGCCTGTGGGCAAAGGTCCTG
CTGCTCAACGAAATGGTCCGCCAGGACGTGGCGCCGGTGGAACTGGCGCGCCGGCTGGGAACGCGCAAGCAGGAAGTCAC
CCGCATCATGGACCTGGGCCATGCCACCAAGATCGATACCATTGCTGCCGCGCTTGCCAGCCTAGGGCGAGAGCTGAGCT
TGTCGGTGCGTTAA
ATGCGCTACGCCGCTCGAATCGAACCGGATGGCAACGTTTTCATGGTGTCGTTCCGCGACATCCCCGAAGCTCTGACGGC
TGCGGATACCCGCGAGGAAGCCGAGGCCGCAGCGGCCGATGCATTGCGCACGGCCATGGACTTCTATTTCGAGGATCGAC
GGGCCGTACCCCTGCCGTCCAAGGCCCAGGCCGGTGAGGTCCTGGTTGAACTACCTGCCAGCCTGTGGGCAAAGGTCCTG
CTGCTCAACGAAATGGTCCGCCAGGACGTGGCGCCGGTGGAACTGGCGCGCCGGCTGGGAACGCGCAAGCAGGAAGTCAC
CCGCATCATGGACCTGGGCCATGCCACCAAGATCGATACCATTGCTGCCGCGCTTGCCAGCCTAGGGCGAGAGCTGAGCT
TGTCGGTGCGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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