Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/- |
| Location | 1249700..1250289 | Replicon | chromosome |
| Accession | NZ_CP033966 | ||
| Organism | Pigmentiphaga sp. H8 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | EGT29_RS05915 | Protein ID | WP_124688146.1 |
| Coordinates | 1249700..1249954 (+) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | EGT29_RS05920 | Protein ID | WP_124688147.1 |
| Coordinates | 1249951..1250289 (+) | Length | 113 a.a. |
Genomic Context
Location: 1247815..1249242 (1428 bp)
Type: Others
Protein ID: WP_124688145.1
Type: Others
Protein ID: WP_124688145.1
Location: 1249700..1249954 (255 bp)
Type: Toxin
Protein ID: WP_124688146.1
Type: Toxin
Protein ID: WP_124688146.1
Location: 1249951..1250289 (339 bp)
Type: Antitoxin
Protein ID: WP_124688147.1
Type: Antitoxin
Protein ID: WP_124688147.1
Location: 1251905..1252498 (594 bp)
Type: Others
Protein ID: WP_124688149.1
Type: Others
Protein ID: WP_124688149.1
Location: 1252819..1253262 (444 bp)
Type: Others
Protein ID: WP_124688150.1
Type: Others
Protein ID: WP_124688150.1
Location: 1253479..1254510 (1032 bp)
Type: Others
Protein ID: WP_124688151.1
Type: Others
Protein ID: WP_124688151.1
Location: 1244927..1247668 (2742 bp)
Type: Others
Protein ID: WP_124688144.1
Type: Others
Protein ID: WP_124688144.1
Location: 1250847..1251293 (447 bp)
Type: Others
Protein ID: WP_202865591.1
Type: Others
Protein ID: WP_202865591.1
Location: 1251290..1251616 (327 bp)
Type: Others
Protein ID: WP_124688148.1
Type: Others
Protein ID: WP_124688148.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGT29_RS05890 | 1244927..1247668 | - | 2742 | WP_124688144.1 | bifunctional acetate--CoA ligase family protein/GNAT family N-acetyltransferase | - |
| EGT29_RS05895 | 1247815..1249242 | + | 1428 | WP_124688145.1 | glutamate--tRNA ligase | - |
| EGT29_RS05915 | 1249700..1249954 | + | 255 | WP_124688146.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| EGT29_RS05920 | 1249951..1250289 | + | 339 | WP_124688147.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| EGT29_RS28640 | 1250847..1251293 | - | 447 | WP_202865591.1 | zinc ribbon domain-containing protein | - |
| EGT29_RS05945 | 1251290..1251616 | - | 327 | WP_124688148.1 | hypothetical protein | - |
| EGT29_RS05950 | 1251905..1252498 | + | 594 | WP_124688149.1 | YdeI/OmpD-associated family protein | - |
| EGT29_RS05955 | 1252819..1253262 | + | 444 | WP_124688150.1 | hypothetical protein | - |
| EGT29_RS05960 | 1253479..1254510 | + | 1032 | WP_124688151.1 | serine hydrolase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9413.93 Da Isoelectric Point: 10.4777
>T114744 WP_124688146.1 NZ_CP033966:1249700-1249954 [Pigmentiphaga sp. H8]
MKAKHQRTLELIFSRPTPGGVKWSAIVGLFHELGAEFVEREGSRVAVVFRDQVMVLHRPHPTPDVDKGAVASIRKWLEES
GVKP
MKAKHQRTLELIFSRPTPGGVKWSAIVGLFHELGAEFVEREGSRVAVVFRDQVMVLHRPHPTPDVDKGAVASIRKWLEES
GVKP
Download Length: 255 bp
>T114744 NZ_CP033966:1249700-1249954 [Pigmentiphaga sp. H8]
ATGAAAGCCAAGCATCAGCGCACGCTGGAACTGATCTTCTCCCGTCCGACCCCAGGCGGAGTGAAGTGGTCGGCCATAGT
GGGGCTGTTTCATGAGCTTGGAGCGGAGTTTGTCGAACGAGAGGGATCCCGGGTCGCAGTCGTTTTTCGGGATCAGGTAA
TGGTCCTACATCGCCCTCATCCGACTCCCGACGTAGACAAAGGCGCTGTTGCTTCTATCCGCAAATGGCTCGAAGAATCA
GGAGTCAAGCCATGA
ATGAAAGCCAAGCATCAGCGCACGCTGGAACTGATCTTCTCCCGTCCGACCCCAGGCGGAGTGAAGTGGTCGGCCATAGT
GGGGCTGTTTCATGAGCTTGGAGCGGAGTTTGTCGAACGAGAGGGATCCCGGGTCGCAGTCGTTTTTCGGGATCAGGTAA
TGGTCCTACATCGCCCTCATCCGACTCCCGACGTAGACAAAGGCGCTGTTGCTTCTATCCGCAAATGGCTCGAAGAATCA
GGAGTCAAGCCATGA
Antitoxin
Download Length: 113 a.a. Molecular weight: 12315.94 Da Isoelectric Point: 5.1716
>AT114744 WP_124688147.1 NZ_CP033966:1249951-1250289 [Pigmentiphaga sp. H8]
MKNVMNIDGYQAVIQFDPEIQMFRGEFVGLNGGADFYASDVPGLVREGKASLKVFLDICEERGIEPRKHFSGKFNLRVSS
KVHEAASIAAAAEGESLNQWIAKTIEEAVSTH
MKNVMNIDGYQAVIQFDPEIQMFRGEFVGLNGGADFYASDVPGLVREGKASLKVFLDICEERGIEPRKHFSGKFNLRVSS
KVHEAASIAAAAEGESLNQWIAKTIEEAVSTH
Download Length: 339 bp
>AT114744 NZ_CP033966:1249951-1250289 [Pigmentiphaga sp. H8]
ATGAAGAATGTGATGAACATCGACGGCTATCAAGCAGTTATCCAATTTGACCCGGAAATCCAGATGTTCCGGGGAGAGTT
CGTCGGACTCAATGGTGGGGCCGACTTCTACGCGTCGGATGTTCCCGGCCTCGTTCGCGAAGGGAAGGCATCGCTCAAGG
TCTTTCTCGATATATGTGAGGAGCGTGGCATTGAGCCGCGCAAGCACTTTTCAGGGAAGTTCAATCTGCGTGTTTCCTCG
AAGGTACACGAAGCCGCGAGCATTGCCGCGGCGGCGGAAGGCGAAAGCCTCAATCAATGGATTGCGAAGACCATTGAAGA
GGCGGTGTCCACGCATTGA
ATGAAGAATGTGATGAACATCGACGGCTATCAAGCAGTTATCCAATTTGACCCGGAAATCCAGATGTTCCGGGGAGAGTT
CGTCGGACTCAATGGTGGGGCCGACTTCTACGCGTCGGATGTTCCCGGCCTCGTTCGCGAAGGGAAGGCATCGCTCAAGG
TCTTTCTCGATATATGTGAGGAGCGTGGCATTGAGCCGCGCAAGCACTTTTCAGGGAAGTTCAATCTGCGTGTTTCCTCG
AAGGTACACGAAGCCGCGAGCATTGCCGCGGCGGCGGAAGGCGAAAGCCTCAATCAATGGATTGCGAAGACCATTGAAGA
GGCGGTGTCCACGCATTGA