Detailed information of TA system TA114743

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 1000659..1001353
• Replicon: chromosome
• Accession: NZ_CP033966
• Organism: Pigmentiphaga sp. H8

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: EGT29_RS04790
• Protein ID: WP_124687942.1
• Coordinates: 1000659..1001018 (+)
• Length: 120 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: EGT29_RS04795
• Protein ID: WP_124687943.1
• Coordinates: 1001021..1001353 (+)
• Length: 111 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGT29_RS04770	997383..997814	-	432	WP_087840934.1	type VI secretion system baseplate subunit TssE	-
EGT29_RS04775	997861..998355	-	495	WP_124687939.1	type VI secretion system tube protein Hcp	-
EGT29_RS04780	998378..999865	-	1488	WP_124687940.1	type VI secretion system contractile sheath large subunit	-
EGT29_RS04785	999892..1000410	-	519	WP_124687941.1	type VI secretion system contractile sheath small subunit	-
EGT29_RS04790	1000659..1001018	+	360	WP_124687942.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EGT29_RS04795	1001021..1001353	+	333	WP_124687943.1	helix-turn-helix domain-containing protein	Antitoxin
EGT29_RS04800	1001361..1002449	-	1089	WP_124687944.1	type VI secretion system protein TssA	-
EGT29_RS04805	1002466..1006047	-	3582	WP_124687945.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (17-110)

Antitoxin

• Cro/C1-type helix-turn-helix domain (35-91)

Sequences

Toxin

Protein

• Length: 120 a.a.
• Molecular weight: 13410.57 Da
• Isoelectric Point: 10.2630

>T114743 WP_124687942.1 NZ_CP033966:1000659-1001018 [Pigmentiphaga sp. H8]
MRPIELKPLRWVASSRKDLRAMPEAVQDVFGYALYLAQGGQKHPQAKPLKGFGGSGVLEVVEDFLGDTYRAVYTIRYRSA
VYVLHCFQKKSVRGVATPRPDIELIRARLKSVDAYEARA

Nucleotide

• Length: 360 bp

>T114743 NZ_CP033966:1000659-1001018 [Pigmentiphaga sp. H8]
ATGAGGCCGATCGAGTTGAAGCCGCTGCGATGGGTCGCATCCTCCAGAAAGGACCTTCGCGCGATGCCGGAAGCCGTGCA
GGATGTGTTTGGCTATGCCCTCTACCTGGCCCAGGGCGGGCAGAAGCACCCGCAGGCGAAGCCGCTCAAAGGATTTGGCG
GCTCCGGTGTGCTCGAGGTGGTCGAAGATTTCCTGGGCGACACCTACCGTGCTGTCTATACGATCCGTTATCGATCGGCC
GTCTATGTACTACATTGTTTTCAGAAGAAGTCCGTGCGTGGAGTTGCCACGCCCAGACCGGACATCGAACTGATCAGGGC
CCGGTTGAAGAGTGTGGACGCATACGAGGCCAGAGCATGA

Antitoxin

Protein

• Length: 111 a.a.
• Molecular weight: 12320.27 Da
• Isoelectric Point: 8.0343

>AT114743 WP_124687943.1 NZ_CP033966:1001021-1001353 [Pigmentiphaga sp. H8]
MSDIKDFPVEQGTESVYADLGYPDASDMQVKAELAREIAQILIDRRLTQQHAATILGMPQPKLSEMLRGKFRGISQAKMI
ECLNRLGRDVDIVVRKAKRQAEGHTQVVVV

Nucleotide

• Length: 333 bp

>AT114743 NZ_CP033966:1001021-1001353 [Pigmentiphaga sp. H8]
ATGAGTGACATCAAGGATTTTCCCGTTGAGCAAGGCACGGAAAGTGTCTACGCGGATCTGGGGTACCCGGACGCCTCGGA
CATGCAGGTCAAGGCCGAACTGGCCAGGGAAATCGCGCAGATCCTGATAGACCGCAGGTTGACCCAGCAACATGCCGCCA
CCATCCTGGGCATGCCGCAACCCAAGCTGTCCGAGATGTTGCGCGGTAAGTTCAGGGGCATCAGCCAAGCGAAGATGATC
GAATGTCTGAACCGGCTGGGCCGCGACGTGGATATCGTCGTCAGGAAAGCCAAGCGTCAGGCGGAAGGACATACGCAGGT
CGTCGTGGTCTGA