Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 759565..760424 Replicon chromosome
Accession NZ_CP033966
Organism Pigmentiphaga sp. H8

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag EGT29_RS03705 Protein ID WP_124687750.1
Coordinates 760026..760424 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag EGT29_RS03700 Protein ID WP_124687749.1
Coordinates 759565..760029 (+) Length 155 a.a.

Genomic Context

EGT29_RS03685EGT29_RS03690EGT29_RS03700EGT29_RS03705EGT29_RS03720EGT29_RS03695EGT29_RS03710EGT29_RS03715EGT29_RS03725EGT29_RS03730
Location: 755162..756595 (1434 bp)
Type: Others
Protein ID: WP_124687746.1
Location: 756742..757581 (840 bp)
Type: Others
Protein ID: WP_124687747.1
Location: 759565..760029 (465 bp)
Type: Antitoxin
Protein ID: WP_124687749.1
Location: 760026..760424 (399 bp)
Type: Toxin
Protein ID: WP_124687750.1
Location: 762523..763002 (480 bp)
Type: Others
Protein ID: WP_124687753.1
Location: 757623..759077 (1455 bp)
Type: Others
Protein ID: WP_124687748.1
Location: 760429..761751 (1323 bp)
Type: Others
Protein ID: WP_124687751.1
Location: 761748..762407 (660 bp)
Type: Others
Protein ID: WP_124687752.1
Location: 763009..763869 (861 bp)
Type: Others
Protein ID: WP_124687754.1
Location: 763885..764748 (864 bp)
Type: Others
Protein ID: WP_124687755.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EGT29_RS03685755162..756595+1434WP_124687746.1sodium:solute symporter family protein-
EGT29_RS03690756742..757581+840WP_124687747.1ferritin-like domain-containing protein-
EGT29_RS03695757623..759077-1455WP_124687748.1DegQ family serine endoprotease-
EGT29_RS03700759565..760029+465WP_124687749.1helix-turn-helix domain-containing proteinAntitoxin
EGT29_RS03705760026..760424+399WP_124687750.1hypothetical proteinToxin
EGT29_RS03710760429..761751-1323WP_124687751.1sensor histidine kinase N-terminal domain-containing protein-
EGT29_RS03715761748..762407-660WP_124687752.1response regulator-
EGT29_RS03720762523..763002+480WP_124687753.1D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase-
EGT29_RS03725763009..763869-861WP_124687754.1SPOR domain-containing protein-
EGT29_RS03730763885..764748-864WP_124687755.1type III pantothenate kinase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SinI-like, DNA-binding domain

(83-129)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 15366.69 Da        Isoelectric Point: 8.0518

>T114741 WP_124687750.1 NZ_CP033966:760026-760424 [Pigmentiphaga sp. H8]
MRHSPFTVIYDACVLYPAPLRDFLMWLGLSGRFRARWSREIHEEWKRNLLLNRQDLTRAQLDRTSDLMDRAIPDEFIDNL
FDLDAAAVVSAAQRQRAQLVHPSIDVDRYLDILLRQGLVQTAKALATYRGIL

Download         Length: 399 bp

>T114741 NZ_CP033966:760026-760424 [Pigmentiphaga sp. H8]
ATGAGGCATTCCCCCTTCACGGTCATCTACGATGCATGCGTGCTTTATCCCGCGCCGTTGAGAGACTTCCTGATGTGGTT
GGGGTTATCAGGTCGGTTTCGGGCGCGATGGAGTCGCGAGATCCACGAGGAATGGAAGCGCAACCTGCTGCTTAATCGGC
AGGATCTGACGCGCGCGCAATTGGATCGAACCTCTGACTTGATGGATCGTGCCATTCCGGACGAGTTCATCGACAATCTG
TTCGATCTCGATGCGGCCGCGGTAGTGTCTGCCGCGCAGCGTCAGCGCGCGCAGCTTGTTCATCCCTCTATCGATGTCGA
CCGTTACCTGGACATCCTGCTCCGGCAGGGATTGGTGCAGACCGCGAAGGCGCTGGCGACGTATCGCGGCATCCTTTGA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17311.94 Da        Isoelectric Point: 6.9925

>AT114741 WP_124687749.1 NZ_CP033966:759565-760029 [Pigmentiphaga sp. H8]
MVTAPSKMMLPVEREVQAAVQGQRALAAYLATRVETQRIQIFDDKNQAHQVELPTSALRLLVDILAELADGNAVRVVPVH
AELTTQEAADMLNVSRPHLVKLLEDGALPFHRTGKHRRVRFADLMRYKETRDLAAEQAMGELARQSQELKMGYE

Download         Length: 465 bp

>AT114741 NZ_CP033966:759565-760029 [Pigmentiphaga sp. H8]
ATGGTCACCGCTCCGTCCAAGATGATGCTGCCCGTCGAGCGGGAAGTTCAGGCCGCCGTGCAAGGTCAGCGTGCACTGGC
TGCCTATCTGGCGACGCGTGTCGAAACGCAGCGGATTCAAATCTTCGACGATAAGAACCAGGCTCATCAGGTCGAGCTGC
CTACCTCAGCGCTGCGCCTGCTGGTGGACATACTGGCCGAACTGGCCGATGGCAATGCGGTGAGGGTCGTGCCTGTTCAC
GCCGAACTGACCACCCAGGAGGCCGCGGACATGCTCAATGTTTCGCGCCCGCATCTGGTCAAGCTATTGGAGGATGGCGC
GTTGCCTTTTCACCGGACGGGCAAGCATCGCCGCGTGCGGTTTGCCGATCTGATGCGGTACAAGGAGACGCGTGATCTCG
CCGCCGAGCAGGCCATGGGCGAACTTGCGCGGCAGTCGCAGGAGTTGAAGATGGGGTATGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References