Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1970348..1970493 Replicon chromosome
Accession NZ_CP033946
Organism Klebsiella pneumoniae subsp. pneumoniae strain ARLG-3135

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1970384..1970486 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1970348..1970493 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EG819_RS09760 1965478..1967538 + 2061 WP_004151449.1 oligopeptidase B -
EG819_RS09765 1967542..1968201 - 660 WP_002911407.1 exodeoxyribonuclease X -
EG819_RS09770 1968280..1968510 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EG819_RS09775 1968623..1968997 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EG819_RS09780 1969001..1969870 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
EG819_RS09785 1969887..1970225 + 339 WP_002911404.1 YebY family protein -
- 1970348..1970493 - 146 - - Antitoxin
- 1970384..1970486 + 103 - - Toxin
EG819_RS28280 1970862..1971005 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EG819_RS09795 1971110..1972078 - 969 WP_004151446.1 VirK/YbjX family protein -
EG819_RS09800 1972235..1972888 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
EG819_RS09805 1972885..1973076 - 192 WP_002911395.1 YebW family protein -
EG819_RS09810 1973174..1973413 - 240 WP_002911393.1 YebV family protein -
EG819_RS09815 1973529..1974962 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1899785..1987890 88105


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T114661 NZ_CP033946:1970384-1970486 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT114661 NZ_CP033946:c1970493-1970348 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References