Detailed information of TA system TA114650

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 2708588..2709136
• Replicon: chromosome
• Accession: NZ_CP033917
• Organism: Chryseobacterium sp. G0201

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: EG348_RS12205
• Protein ID: WP_123983380.1
• Coordinates: 2708588..2708887 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: EG348_RS12210
• Protein ID: WP_123983381.1
• Coordinates: 2708888..2709136 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EG348_RS12185	2703998..2704576	-	579	WP_123983377.1	adenylate kinase	-
EG348_RS12190	2704731..2705285	-	555	WP_072412416.1	hypoxanthine phosphoribosyltransferase	-
EG348_RS12195	2705938..2707527	+	1590	WP_123983378.1	ATP-binding cassette domain-containing protein	-
EG348_RS12200	2707594..2708529	-	936	WP_123983379.1	alpha/beta fold hydrolase	-
EG348_RS12205	2708588..2708887	-	300	WP_123983380.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EG348_RS12210	2708888..2709136	-	249	WP_123983381.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
EG348_RS12215	2709245..2710288	-	1044	WP_123983382.1	hypothetical protein	-
EG348_RS12220	2710459..2711745	+	1287	WP_123983383.1	adenylosuccinate synthase	-
EG348_RS12225	2711988..2712821	-	834	WP_123983384.1	N-acetylmuramidase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-92)

Antitoxin

• Antitoxin ParD (1-80)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 12047.69 Da
• Isoelectric Point: 6.2355

>T114650 WP_123983380.1 NZ_CP033917:c2708887-2708588 [Chryseobacterium sp. G0201]
MKYKISKEASNDLEKIWLYTFETWSVKQADHYFDLLMNEIEYLSENPTSGKDYGEIRKGYFRSRVKSHFIFYKINLKNEE
IEIIRILHQQMDISSRLDE

Nucleotide

• Length: 300 bp

>T114650 NZ_CP033917:c2708887-2708588 [Chryseobacterium sp. G0201]
ATGAAATACAAAATCAGTAAAGAAGCATCAAATGATTTAGAAAAAATCTGGCTTTACACCTTCGAAACTTGGTCAGTAAA
ACAGGCAGATCATTATTTTGATTTGCTCATGAATGAAATTGAGTATTTATCTGAGAATCCAACATCCGGAAAAGATTACG
GTGAAATAAGAAAAGGATATTTCCGTTCAAGGGTGAAATCTCATTTTATATTTTACAAAATCAATCTTAAAAATGAAGAA
ATTGAAATTATAAGAATTCTTCATCAACAAATGGATATTTCATCAAGATTGGATGAATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9498.71 Da
• Isoelectric Point: 8.5341

>AT114650 WP_123983381.1 NZ_CP033917:c2709136-2708888 [Chryseobacterium sp. G0201]
MAKNTSILLGDYFDNFISQQIKSGKYSSASEVVRTALRMFEHEESKKTELINELKKGEKSGFVENFDRKEFLKNLHQKHS
AD

Nucleotide

• Length: 249 bp

>AT114650 NZ_CP033917:c2709136-2708888 [Chryseobacterium sp. G0201]
ATGGCAAAAAACACATCCATATTATTAGGAGATTATTTTGACAACTTTATTAGTCAACAGATTAAGTCTGGCAAATACTC
TTCGGCAAGTGAAGTTGTAAGAACAGCTTTAAGAATGTTTGAACATGAGGAATCTAAGAAAACAGAATTAATCAACGAAT
TAAAAAAAGGTGAAAAATCTGGTTTTGTTGAAAATTTTGACCGTAAAGAATTTTTGAAAAATCTTCATCAAAAACATTCT
GCTGACTAA