Detailed information of TA system TA114374

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/ElaA-DUF1778
• Location: 44485..45224
• Replicon: plasmid unnamed2
• Accession: NZ_CP033798
• Organism: Enterobacter roggenkampii strain FDAARGOS_523

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: A0A9E6WPH7
• Locus tag: EGY04_RS00625
• Protein ID: WP_013087269.1
• Coordinates: 44739..45224 (+)
• Length: 162 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: A0A9E6WPN8
• Locus tag: EGY04_RS00620
• Protein ID: WP_007869691.1
• Coordinates: 44485..44751 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGY04_RS00585	40372..40614	+	243	WP_008502222.1	hypothetical protein	-
EGY04_RS00595	40948..41715	+	768	WP_008502221.1	conjugal transfer protein TraX	-
EGY04_RS00600	41737..41970	-	234	WP_008502220.1	DUF2767 family protein	-
EGY04_RS00610	42819..43832	-	1014	WP_123922227.1	replication initiation protein	-
EGY04_RS00620	44485..44751	+	267	WP_007869691.1	DUF1778 domain-containing protein	Antitoxin
EGY04_RS00625	44739..45224	+	486	WP_013087269.1	GNAT family N-acetyltransferase	Toxin
EGY04_RS00630	45420..46823	+	1404	WP_001567368.1	ISNCY-like element ISKpn21 family transposase	-
EGY04_RS00635	46852..47484	-	633	WP_001567369.1	hypothetical protein	-
EGY04_RS00640	47714..49059	+	1346	Protein_48	ISNCY family transposase	-
EGY04_RS00645	49243..49359	-	117	Protein_49	transposase domain-containing protein	-
EGY04_RS25690	49304..49567	-	264	WP_004118209.1	transposase	-
EGY04_RS25695	49582..49845	+	264	WP_148088625.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..103835	103835

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Protein of unknown function DUF2829 (2-69)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 162 a.a.
• Molecular weight: 20782.22 Da
• Isoelectric Point: 13.0068

>T114374 WP_013087269.1 NZ_CP033798:44739-45224 [Enterobacter roggenkampii]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KK

Nucleotide

• Length: 486 bp

>T114374 NZ_CP033798:44739-45224 [Enterobacter roggenkampii]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 11425.51 Da
• Isoelectric Point: 12.7445

>AT114374 WP_007869691.1 NZ_CP033798:44485-44751 [Enterobacter roggenkampii]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKK

Nucleotide

• Length: 267 bp

>AT114374 NZ_CP033798:44485-44751 [Enterobacter roggenkampii]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAA