Detailed information of TA system TA114373

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 28474..28993
• Replicon: plasmid unnamed1
• Accession: NZ_CP033797
• Organism: Enterobacter roggenkampii strain FDAARGOS_523

Toxin (Protein)

• Gene name: parE
• Uniprot ID: A0A9E7BHM1
• Locus tag: EGY04_RS00220
• Protein ID: WP_047389778.1
• Coordinates: 28474..28758 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A9E7BH21
• Locus tag: EGY04_RS00225
• Protein ID: WP_047389775.1
• Coordinates: 28751..28993 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EGY04_RS00185	24667..25470	-	804	WP_010454871.1	IS21-like element ISPst3 family helper ATPase IstB	-
EGY04_RS00190	25463..25945	-	483	Protein_37	IS21 family transposase	-
EGY04_RS00195	25997..26692	-	696	WP_047389784.1	IS6-like element ISEas1 family transposase	-
EGY04_RS00205	27003..27305	+	303	WP_052132604.1	hypothetical protein	-
EGY04_RS00210	27456..28076	+	621	WP_047389782.1	ParA family protein	-
EGY04_RS00215	28115..28342	+	228	WP_047389780.1	DNA partition complex ParG	-
EGY04_RS00220	28474..28758	-	285	WP_047389778.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
EGY04_RS00225	28751..28993	-	243	WP_047389775.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
EGY04_RS00235	30048..30290	+	243	WP_052132603.1	hypothetical protein	-
EGY04_RS00240	31107..31367	-	261	WP_047389771.1	hypothetical protein	-
EGY04_RS00245	31478..32296	-	819	WP_040080118.1	SprT-like domain-containing protein	-
EGY04_RS00250	32299..32532	-	234	WP_047389767.1	antirestriction protein ArdR	-
EGY04_RS00255	32743..33012	-	270	WP_044715198.1	hypothetical protein	-
EGY04_RS00260	33061..33516	-	456	WP_044715196.1	H-NS histone family protein	-
EGY04_RS00265	33535..33744	-	210	WP_044715194.1	hemolysin expression modulator Hha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..53756	53756

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Cro/C1-type helix-turn-helix domain (8-62)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 13999.79 Da
• Isoelectric Point: 5.5500

>T114373 WP_047389778.1 NZ_CP033797:c28758-28474 [Enterobacter roggenkampii]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Nucleotide

• Length: 285 bp

>T114373 NZ_CP033797:c28758-28474 [Enterobacter roggenkampii]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 11939.32 Da
• Isoelectric Point: 5.5500

>AT114373 WP_047389775.1 NZ_CP033797:c28993-28751 [Enterobacter roggenkampii]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Nucleotide

• Length: 243 bp

>AT114373 NZ_CP033797:c28993-28751 [Enterobacter roggenkampii]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTT