Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2686726..2686871 Replicon chromosome
Accession NZ_CP033777
Organism Klebsiella pneumoniae strain FDAARGOS_531

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2686762..2686864 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2686726..2686871 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EGX99_RS15305 2681856..2683916 + 2061 WP_004151449.1 oligopeptidase B -
EGX99_RS15310 2683920..2684579 - 660 WP_080893182.1 exodeoxyribonuclease X -
EGX99_RS15315 2684658..2684888 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EGX99_RS15320 2685001..2685375 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EGX99_RS15325 2685379..2686248 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
EGX99_RS15330 2686265..2686603 + 339 WP_016529031.1 YebY family protein -
- 2686726..2686871 - 146 - - Antitoxin
- 2686762..2686864 + 103 - - Toxin
EGX99_RS29035 2687240..2687383 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EGX99_RS15340 2687488..2688456 - 969 WP_014907334.1 VirK/YbjX family protein -
EGX99_RS15345 2688613..2689266 + 654 WP_023280291.1 protein-serine/threonine phosphatase -
EGX99_RS15350 2689263..2689454 - 192 WP_002911395.1 YebW family protein -
EGX99_RS15355 2689552..2689791 - 240 WP_002911393.1 YebV family protein -
EGX99_RS15360 2689907..2691340 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T114312 NZ_CP033777:2686762-2686864 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT114312 NZ_CP033777:c2686871-2686726 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References