Detailed information of TA system TA114179

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/MazF(toxin)
• Location: 1715675..1716204
• Replicon: chromosome
• Accession: NZ_CP033735
• Organism: Staphylococcus cohnii strain FDAARGOS_538

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: -
• Locus tag: EGX68_RS08815
• Protein ID: WP_103211251.1
• Coordinates: 1715675..1716037 (-)
• Length: 121 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: A0A6N7Y6B0
• Locus tag: EGX68_RS08820
• Protein ID: WP_019468009.1
• Coordinates: 1716034..1716204 (-)
• Length: 57 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• mRNA interferase PemK-like (3-109)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 121 a.a.
• Molecular weight: 13621.72 Da
• Isoelectric Point: 9.8654

>T114179 WP_103211251.1 NZ_CP033735:c1716037-1715675 [Staphylococcus cohnii]
MMRRGDVYLADLSPVQGSEQGGIRPVVIIQNDTGNKYSPTVIVAAITGRINKAKIPTHVEIEKSKYKLDKDSVILLEQIR
TLDKNRLKEKLTYLSEEKMQEVNNAIDISLGLHNIRNYRT

Nucleotide

• Length: 363 bp

>T114179 NZ_CP033735:c1716037-1715675 [Staphylococcus cohnii]
ATGATGAGAAGAGGAGACGTTTATTTAGCTGATTTGTCACCAGTACAGGGTTCTGAACAAGGGGGAATAAGACCCGTAGT
CATTATACAAAATGATACTGGTAACAAGTATAGTCCTACCGTAATTGTAGCTGCAATTACAGGTAGGATTAATAAGGCTA
AAATACCTACACATGTAGAAATAGAAAAAAGCAAGTATAAACTCGACAAGGATTCTGTTATATTGTTAGAGCAAATACGG
ACTTTAGATAAAAATAGATTAAAAGAAAAGTTGACATATTTATCTGAAGAAAAAATGCAAGAAGTTAATAATGCTATAGA
TATTAGCCTTGGTTTACATAATATTAGAAATTATAGAACATAA

Antitoxin

Protein

• Length: 57 a.a.
• Molecular weight: 6359.02 Da
• Isoelectric Point: 4.0121

>AT114179 WP_019468009.1 NZ_CP033735:c1716204-1716034 [Staphylococcus cohnii]
MASFNQNRNHSIEQLLKEGYSQMADLNLSLAAEAFPFECEACDCNEVYIISKNNNE

Nucleotide

• Length: 171 bp

>AT114179 NZ_CP033735:c1716204-1716034 [Staphylococcus cohnii]
ATGGCAAGTTTTAATCAAAACAGAAATCATAGTATTGAACAACTTTTAAAAGAAGGCTATTCTCAAATGGCTGACTTGAA
TCTCTCCCTTGCGGCCGAAGCATTTCCATTTGAATGTGAAGCTTGCGATTGCAATGAAGTCTACATTATATCTAAGAATA
ACAATGAATGA

Structures

Antitoxin

• AlphaFold DB: A0A6N7Y6B0