Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1822728..1823348 Replicon chromosome
Accession NZ_CP033711
Organism Yersinia pseudotuberculosis strain FDAARGOS_582

Toxin (Protein)


Gene name Hha Uniprot ID Q66DR5
Locus tag EGX44_RS09000 Protein ID WP_002208622.1
Coordinates 1823145..1823348 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID Q66DR4
Locus tag EGX44_RS08995 Protein ID WP_002218472.1
Coordinates 1822728..1823096 (+) Length 123 a.a.

Genomic Context

EGX44_RS08980EGX44_RS08985EGX44_RS08990EGX44_RS08995EGX44_RS09000EGX44_RS09010EGX44_RS09020EGX44_RS09015EGX44_RS09025EGX44_RS09030
Location: 1820932..1821192 (261 bp)
Type: Others
Protein ID: WP_002208617.1
Location: 1821208..1821351 (144 bp)
Type: Others
Protein ID: WP_002208618.1
Location: 1822216..1822569 (354 bp)
Type: Others
Protein ID: WP_002208619.1
Location: 1822728..1823096 (369 bp)
Type: Antitoxin
Protein ID: WP_002218472.1
Location: 1823145..1823348 (204 bp)
Type: Toxin
Protein ID: WP_002208622.1
Location: 1824254..1824643 (390 bp)
Type: Others
Protein ID: WP_002208623.1
Location: 1825557..1826417 (861 bp)
Type: Others
Protein ID: WP_002208625.1
Location: 1824779..1825300 (522 bp)
Type: Others
Protein ID: WP_011191872.1
Location: 1826679..1827968 (1290 bp)
Type: Others
Protein ID: WP_002228344.1
Location: 1828008..1828346 (339 bp)
Type: Others
Protein ID: WP_002208627.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EGX44_RS089801820932..1821192+261WP_002208617.1type B 50S ribosomal protein L31-
EGX44_RS089851821208..1821351+144WP_002208618.1type B 50S ribosomal protein L36-
EGX44_RS089901822216..1822569+354WP_002208619.1hypothetical protein-
EGX44_RS089951822728..1823096+369WP_002218472.1Hha toxicity modulator TomBAntitoxin
EGX44_RS090001823145..1823348+204WP_002208622.1expression modulating protein YmoAToxin
EGX44_RS090101824254..1824643+390WP_002208623.1MGMT family protein-
EGX44_RS090151824779..1825300-522WP_011191872.1YbaY family lipoprotein-
EGX44_RS090201825557..1826417+861WP_002208625.1acyl-CoA thioesterase II-
EGX44_RS090251826679..1827968-1290WP_002228344.1ammonium transporter AmtB-
EGX44_RS090301828008..1828346-339WP_002208627.1P-II family nitrogen regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8063.31 Da        Isoelectric Point: 6.4573

>T114116 WP_002208622.1 NZ_CP033711:1823145-1823348 [Yersinia pseudotuberculosis]
MTKTDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPPTVWQHVK

Download         Length: 204 bp

>T114116 NZ_CP033711:1823145-1823348 [Yersinia pseudotuberculosis]
ATGACAAAAACTGACTACCTGATGCGTTTAAGAAAATGTACGACTATCGATACGCTAGAACGTGTAATTGAAAAAAATAA
GTACGAACTTTCTGATGATGAACTGGAATTGTTTTACTCAGCTGCAGACCATCGCCTGGCTGAACTAACGATGAATAAGC
TTTATGATAAAATTCCACCTACTGTATGGCAACATGTGAAATAG

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14215.00 Da        Isoelectric Point: 4.6121

>AT114116 WP_002218472.1 NZ_CP033711:1822728-1823096 [Yersinia pseudotuberculosis]
MDEYSPKRHDIAQLKFLCESLYDEGIATLGDSHHGWINDPTSAINLQLNDLIEHIASFVMSFKIKYPDGSQLSELVEEYL
DDTYTLFSSYGINDPELRRWQKTKEHLFRLFSGEYVCTLMKT

Download         Length: 369 bp

>AT114116 NZ_CP033711:1822728-1823096 [Yersinia pseudotuberculosis]
ATGGATGAGTACTCGCCTAAGCGGCATGACATTGCCCAACTGAAGTTTCTATGTGAAAGCTTGTATGATGAAGGTATTGC
AACTCTTGGCGACAGCCATCATGGCTGGATAAATGACCCAACGTCGGCCATAAACCTTCAACTCAATGATTTGATCGAGC
ATATAGCTTCATTTGTGATGAGTTTTAAAATAAAATACCCGGATGGAAGCCAGCTTTCCGAGTTAGTGGAAGAATATTTA
GACGACACATATACTCTGTTTAGTAGTTATGGAATCAATGATCCTGAATTGCGTCGCTGGCAGAAAACCAAAGAGCATTT
ATTCAGACTTTTCTCAGGGGAATACGTATGTACCCTGATGAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
PDB2K5S

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ66DR4

References