Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /COG5642-COG5654
Location 389902..390902 Replicon chromosome
Accession NZ_CP033711
Organism Yersinia pseudotuberculosis strain FDAARGOS_582

Toxin (Protein)


Gene name - Uniprot ID Q66A68
Locus tag EGX44_RS02420 Protein ID WP_011192520.1
Coordinates 389902..390360 (-) Length 153 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID Q66A69
Locus tag EGX44_RS02425 Protein ID WP_002210982.1
Coordinates 390456..390902 (-) Length 149 a.a.

Genomic Context

EGX44_RS02390EGX44_RS02395EGX44_RS02400EGX44_RS02405EGX44_RS02410EGX44_RS02415EGX44_RS02430EGX44_RS02440EGX44_RS02420EGX44_RS02425EGX44_RS02435EGX44_RS02445
Location: 385716..386381 (666 bp)
Type: Others
Protein ID: WP_002210975.1
Location: 386543..386770 (228 bp)
Type: Others
Protein ID: WP_002210976.1
Location: 386770..387129 (360 bp)
Type: Others
Protein ID: WP_002210977.1
Location: 387214..387456 (243 bp)
Type: Others
Protein ID: WP_002216375.1
Location: 387437..388834 (1398 bp)
Type: Others
Protein ID: WP_012105043.1
Location: 388831..389892 (1062 bp)
Type: Others
Protein ID: WP_012413752.1
Location: 391239..392816 (1578 bp)
Type: Others
Protein ID: WP_011192519.1
Location: 393646..394626 (981 bp)
Type: Others
Protein ID: WP_012413751.1
Location: 389902..390360 (459 bp)
Type: Toxin
Protein ID: WP_011192520.1
Location: 390456..390902 (447 bp)
Type: Antitoxin
Protein ID: WP_002210982.1
Location: 392980..393483 (504 bp)
Type: Others
Protein ID: WP_002210984.1
Location: 394668..395375 (708 bp)
Type: Others
Protein ID: WP_038823925.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EGX44_RS02390385716..386381+666WP_002210975.1phage shock protein PspA-
EGX44_RS02395386543..386770+228WP_002210976.1envelope stress response membrane protein PspB-
EGX44_RS02400386770..387129+360WP_002210977.1envelope stress response membrane protein PspC-
EGX44_RS02405387214..387456+243WP_002216375.1phage shock protein PspD-
EGX44_RS02410387437..388834+1398WP_012105043.1YcjX family protein-
EGX44_RS02415388831..389892+1062WP_012413752.1YcjF family protein-
EGX44_RS02420389902..390360-459WP_011192520.1RES family NAD+ phosphorylaseToxin
EGX44_RS02425390456..390902-447WP_002210982.1DUF2384 domain-containing proteinAntitoxin
EGX44_RS02430391239..392816+1578WP_011192519.1transcriptional regulator TyrR-
EGX44_RS02435392980..393483-504WP_002210984.1thiol peroxidase-
EGX44_RS02440393646..394626+981WP_012413751.1L-Ala-D/L-Glu epimerase-
EGX44_RS02445394668..395375-708WP_038823925.1murein tripeptide amidase MpaA-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(2-147)

Antitoxin

Antitoxin Xre

(15-147)


Sequences

Toxin        


Download         Length: 153 a.a.        Molecular weight: 17008.41 Da        Isoelectric Point: 4.8732

>T114107 WP_011192520.1 NZ_CP033711:c390360-389902 [Yersinia pseudotuberculosis]
MTLYRIVMRRYLASAWTGYGAEIYGGRWNHKGHAAIYLASSISLAMLETLAHIQDSSTLSEFELFQIEISDSSIMLLQPQ
DWPTDWRSDPAPVATMDVGTEWLESESSLGLLVPSTLVPSENNLLVNPHHKDFPACLASVKPLSFVFDPRLK

Download         Length: 459 bp

>T114107 NZ_CP033711:c390360-389902 [Yersinia pseudotuberculosis]
ATGACGCTATACCGCATTGTTATGCGCCGCTATCTTGCATCGGCATGGACTGGTTACGGCGCTGAAATCTATGGTGGTCG
TTGGAATCATAAAGGCCATGCTGCCATCTATTTAGCCAGCAGTATTTCATTGGCTATGCTCGAAACACTGGCTCATATTC
AGGACAGTTCAACACTCAGCGAATTTGAATTATTCCAAATTGAAATCAGTGACAGCAGTATTATGTTGCTACAGCCGCAG
GACTGGCCCACGGATTGGCGTAGCGATCCGGCACCGGTGGCAACGATGGATGTCGGCACCGAGTGGCTGGAATCAGAATC
CTCGCTAGGCTTACTGGTCCCGTCCACGTTGGTGCCGTCAGAAAACAACCTACTGGTCAATCCTCATCACAAAGATTTTC
CAGCGTGTTTGGCCAGCGTCAAACCGCTCTCTTTTGTCTTTGATCCACGGTTAAAATAG

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16401.94 Da        Isoelectric Point: 9.7155

>AT114107 WP_002210982.1 NZ_CP033711:c390902-390456 [Yersinia pseudotuberculosis]
MRAYRPNPATKMGTLWREIGLPASRGTILVDSIKMGFSVDVIDSIHLWASMPKAEILRATGIPSRSLTRRRTHDGRFTPE
ESERIARFVRVMDAAVDLFGGDKGKAITWMSTPIKGLGYRSPDSLLETETGALEVCDLIGRLEHGVFT

Download         Length: 447 bp

>AT114107 NZ_CP033711:c390902-390456 [Yersinia pseudotuberculosis]
ATGAGAGCGTACCGCCCAAACCCCGCGACTAAAATGGGAACGCTTTGGCGTGAAATTGGCTTACCCGCCAGCCGCGGCAC
GATATTGGTCGATAGTATCAAAATGGGGTTTTCTGTTGATGTTATCGACAGCATTCATTTATGGGCATCCATGCCTAAAG
CTGAAATATTACGTGCTACCGGTATCCCCAGCCGTAGCCTGACTCGCCGCCGCACACATGATGGCCGTTTTACGCCTGAA
GAAAGCGAGAGAATCGCACGTTTTGTCCGCGTAATGGATGCCGCTGTCGATTTGTTCGGCGGCGATAAAGGTAAAGCCAT
TACCTGGATGTCCACGCCCATCAAAGGATTGGGGTATCGCAGCCCAGACTCCTTACTGGAAACCGAAACTGGCGCACTGG
AAGTGTGTGATTTGATTGGTCGTTTGGAACACGGCGTCTTTACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
AlphaFold DBQ66A68

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0E8XFL1

References