Detailed information of TA system TA113879

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 3934829..3935507
• Replicon: chromosome
• Accession: NZ_CP033622
• Organism: Dickeya zeae strain CE1

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: DWG24_RS17520
• Protein ID: WP_168363480.1
• Coordinates: 3934829..3935260 (-)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: -
• Locus tag: DWG24_RS17525
• Protein ID: WP_038906203.1
• Coordinates: 3935241..3935507 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DWG24_RS17500	3930752..3931468	-	717	WP_168363476.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-
DWG24_RS17505	3931556..3932455	-	900	WP_168363477.1	site-specific tyrosine recombinase XerD	-
DWG24_RS17510	3932719..3934044	+	1326	WP_168363478.1	MHS family MFS transporter	-
DWG24_RS17515	3934222..3934740	+	519	WP_168363479.1	flavodoxin FldB	-
DWG24_RS17520	3934829..3935260	-	432	WP_168363480.1	protein YgfX	Toxin
DWG24_RS17525	3935241..3935507	-	267	WP_038906203.1	FAD assembly factor SdhE	Antitoxin
DWG24_RS17530	3935816..3936796	+	981	WP_168363481.1	tRNA-modifying protein YgfZ	-
DWG24_RS17535	3936873..3937523	-	651	WP_019846261.1	hemolysin III family protein	-
DWG24_RS17540	3937736..3938344	+	609	WP_168363482.1	HD domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (7-79)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16936.61 Da
• Isoelectric Point: 11.7122

>T113879 WP_168363480.1 NZ_CP033622:c3935260-3934829 [Dickeya zeae]
VAQWQCDLRVSWRMQLFSLLTHGFLMLMILLAPWPDGYAPLWLGLVTLVVFDFVRSQRSIKSRQGEISLRGDNQLRWQQR
DWQIVRRPWFMRNGVLLSLRAVDGKGQQRLWLASDSMGSEEWRLLRQQLQQPTLHGTESSRHH

Nucleotide

• Length: 432 bp

>T113879 NZ_CP033622:c3935260-3934829 [Dickeya zeae]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGTATGCAGTTGTTTTCGCTGCTGACGCACGGATTTCTGATGCT
GATGATCCTGCTGGCTCCCTGGCCGGACGGCTACGCACCGCTGTGGCTCGGGTTAGTGACGCTGGTGGTGTTTGACTTTG
TGCGTAGCCAGCGAAGCATCAAATCGCGCCAGGGGGAGATTTCCCTGCGTGGCGATAACCAACTGCGCTGGCAGCAACGT
GACTGGCAGATTGTCCGGCGACCGTGGTTCATGCGCAACGGCGTGTTGTTGTCGCTACGGGCGGTGGATGGTAAAGGGCA
ACAGCGTTTGTGGCTGGCGTCAGACAGTATGGGGAGTGAGGAATGGCGGCTGTTACGTCAACAGCTGCAGCAGCCTACGC
TGCATGGAACGGAATCTTCCCGCCATCATTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10446.96 Da
• Isoelectric Point: 5.5981

>AT113879 WP_038906203.1 NZ_CP033622:c3935507-3935241 [Dickeya zeae]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPGLKRMVSLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT113879 NZ_CP033622:c3935507-3935241 [Dickeya zeae]
ATGGACATCAATAACAAAGCACGTATTCACTGGGCGTGCAGGCGTGGAATGCGCGAACTGGACATCTCTATCATGCCGTT
TTTCGAGCATGAGTACGATACGCTGAGCGACGACGACAAACAGCAGTTTATTCGTCTGCTGCAGTGTGACGATCCCGACC
TGTTTAATTGGTTGATGAACCACGGCGAGCCGGTTGATCCTGGTTTGAAGCGGATGGTTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCAATGTGA