Detailed information of TA system TA113878

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 3701725..3702503
• Replicon: chromosome
• Accession: NZ_CP033622
• Organism: Dickeya zeae strain CE1

Toxin (Protein)

• Gene name: TacT2
• Uniprot ID: -
• Locus tag: DWG24_RS16405
• Protein ID: WP_168363311.1
• Coordinates: 3701725..3702213 (-)
• Length: 163 a.a.

Antitoxin (Protein)

• Gene name: TacA2
• Uniprot ID: -
• Locus tag: DWG24_RS16410
• Protein ID: WP_040002550.1
• Coordinates: 3702210..3702503 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DWG24_RS16395	3698524..3699636	+	1113	WP_168363309.1	reverse transcriptase family protein	-
DWG24_RS16400	3700529..3701632	-	1104	WP_168363310.1	hypothetical protein	-
DWG24_RS16405	3701725..3702213	-	489	WP_168363311.1	GNAT family N-acetyltransferase	Toxin
DWG24_RS16410	3702210..3702503	-	294	WP_040002550.1	DUF1778 domain-containing protein	Antitoxin
DWG24_RS16415	3702966..3704192	-	1227	WP_168363312.1	PD-(D/E)XK nuclease family protein	-
DWG24_RS16420	3704490..3705596	+	1107	WP_168364108.1	ABC transporter substrate-binding protein	-
DWG24_RS16425	3705829..3706356	+	528	WP_168363313.1	AAA family ATPase	-
DWG24_RS16430	3706407..3706802	-	396	WP_168363314.1	helix-turn-helix transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (14-88)

Sequences

Toxin

Protein

• Length: 163 a.a.
• Molecular weight: 17570.42 Da
• Isoelectric Point: 6.0715

>T113878 WP_168363311.1 NZ_CP033622:c3702213-3701725 [Dickeya zeae]
MISVPEPLHAEHAFSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVAMNSAPGRFRRNMPDPI
PVVVLGRLAVDTSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHVLSDEAWEFYLLVGFEPSPIDPMMLMVTLGDLVG
SF

Nucleotide

• Length: 489 bp

>T113878 NZ_CP033622:c3702213-3701725 [Dickeya zeae]
ATGATCTCTGTTCCTGAGCCACTCCACGCCGAACATGCATTTTCCTCGTTCTGTTGCGGTGTGGAGTCTATGGATAACTG
GCTAAAACTACGGGCGATGAAAAATCAGGTCACTGGAGCATCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGTTAG
CGTATTACTCATTGGCTTCCAGTGCTGTAGCAATGAATTCAGCTCCTGGACGTTTTCGCCGAAATATGCCCGATCCTATC
CCGGTCGTGGTGTTGGGGCGGTTGGCTGTGGATACGTCATTGCATGGTCAAGGTGTTGGCCGTGCTCTGGTACGTGATGC
TGGGCTAAGAGTGATTCAGGTTGCTGATACTATCGGCATTCGCGGGATGCTGGTTCATGTGCTGTCTGATGAGGCATGGG
AATTTTATCTACTGGTGGGGTTTGAACCTTCGCCGATAGATCCGATGATGCTGATGGTGACGTTGGGGGATTTAGTTGGG
AGTTTTTAA

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10890.46 Da
• Isoelectric Point: 10.1968

>AT113878 WP_040002550.1 NZ_CP033622:c3702503-3702210 [Dickeya zeae]
MSVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQAPSPN
AALRKTMQTPAPWEQKK

Nucleotide

• Length: 294 bp

>AT113878 NZ_CP033622:c3702503-3702210 [Dickeya zeae]
ATGTCAGTGACGAATAGCGTTTCTGTTAAACGCGAAACATTGAACTTACGGATCAAGCCCGCTGAACGCGATCTGATTGA
TCGTGCTGCGAAGGCCAGAGGAAAAAATCGCACTGATTTTGTCCTCGAAGCTGCTCGCGCCGCCGCAGAGGAAGCCTTGA
TCGATCAGCGCATCATCATGGCAGATCCCGATGCTTATCAGGAATTCCTCGCCCGTTTGGATCAGGCTCCTTCACCGAAT
GCTGCGCTGCGCAAAACCATGCAAACGCCTGCTCCGTGGGAACAGAAAAAATGA