113866

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 1515454..1516798 Replicon chromosome
Accession NZ_CP033622
Organism Dickeya zeae strain CE1

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag DWG24_RS06875 Protein ID WP_168361985.1
Coordinates 1515454..1516410 (-) Length 319 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag DWG24_RS06880 Protein ID WP_033576632.1
Coordinates 1516403..1516798 (-) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DWG24_RS06840 1511159..1511338 + 180 Protein_1311 acetolactate synthase large subunit -
DWG24_RS06845 1511304..1511501 + 198 WP_168361980.1 hypothetical protein -
DWG24_RS06850 1511596..1511865 - 270 WP_168361981.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -
DWG24_RS06855 1511950..1512357 + 408 Protein_1314 AraC family ligand binding domain-containing protein -
DWG24_RS06860 1512430..1512900 - 471 WP_168361982.1 cyanase -
DWG24_RS06865 1512928..1513587 - 660 WP_168361983.1 carbonic anhydrase -
DWG24_RS06870 1513698..1514585 + 888 WP_168361984.1 transcriptional regulator CynR -
DWG24_RS06875 1515454..1516410 - 957 WP_168361985.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
DWG24_RS06880 1516403..1516798 - 396 WP_033576632.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
DWG24_RS06885 1517045..1517339 - 295 Protein_1320 PIN domain-containing protein -
DWG24_RS06890 1517364..1517639 + 276 Protein_1321 baseplate protein -
DWG24_RS06895 1517648..1518067 + 420 WP_168361986.1 phage GP46 family protein -
DWG24_RS06905 1518776..1521226 + 2451 WP_168361987.1 DUF3772 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-302)

Antitoxin

Protein of unknown function DUF6088

(7-114)


Sequences

Toxin        


Download         Length: 319 a.a.        Molecular weight: 36723.20 Da        Isoelectric Point: 5.3283

>T113866 WP_168361985.1 NZ_CP033622:c1516410-1515454 [Dickeya zeae]
MDELTALFPDVADALGIESVSIVEKDYYIVELLRLLRHLTFDTHQLVFAGGTALSKAGISLNRMSEDVDIKLVPTANFLQ
QSSRSQRKNIRKDIIRTITESIVASRVFSFDDDYPKVTRDEYRYNEIPVRYPQMYSQIPCLRPFIKLELMETDLLESSET
RDICSLVTDVTKKGEMVRAFPCATIVSTQAEKLISIMRRTAASMRDLERVEDKSLVRHIYDNFCIVREKGVNVAALTHFI
QECIEQDIARYGNQYPEFCESPVEELKKGLEELASNPVYKMRYQQFLAPMVFGEIRVSWEEAYSCFRQTVLSVLKSYR

Download         Length: 957 bp

>T113866 NZ_CP033622:c1516410-1515454 [Dickeya zeae]
ATGGATGAGTTAACAGCATTATTTCCTGACGTTGCTGATGCACTTGGAATTGAGTCTGTCTCTATAGTGGAGAAAGATTA
TTACATCGTTGAATTATTACGCCTGCTTCGGCATCTGACTTTTGATACGCATCAACTGGTTTTTGCCGGAGGTACAGCGT
TATCAAAAGCAGGAATATCGTTAAACCGGATGTCAGAAGATGTAGATATTAAGCTGGTTCCTACTGCTAATTTTTTGCAA
CAAAGCTCAAGAAGTCAGCGTAAGAATATACGTAAAGATATCATCCGAACGATTACCGAATCGATCGTTGCTTCCAGGGT
TTTTAGTTTTGACGATGACTATCCCAAAGTCACTCGCGATGAATATCGTTACAATGAAATTCCCGTGCGTTATCCGCAAA
TGTATTCACAAATCCCTTGCCTGCGGCCATTTATTAAACTGGAGTTAATGGAAACAGACTTGCTTGAATCATCAGAAACG
CGTGATATTTGCTCATTGGTAACTGATGTCACGAAAAAAGGGGAAATGGTTCGAGCTTTTCCATGTGCCACTATAGTCAG
TACGCAGGCTGAAAAGCTTATCTCGATAATGCGAAGAACAGCTGCAAGTATGCGTGATTTGGAACGAGTAGAGGATAAAT
CACTGGTGCGCCATATCTACGACAATTTTTGTATTGTCAGAGAGAAAGGCGTTAATGTTGCCGCTTTAACCCATTTTATT
CAGGAATGTATTGAGCAAGATATTGCACGTTACGGTAATCAGTATCCTGAGTTCTGCGAATCGCCTGTTGAGGAACTCAA
AAAAGGGCTGGAAGAGCTGGCAAGTAATCCTGTTTATAAAATGCGCTATCAACAATTCTTAGCGCCAATGGTGTTTGGTG
AAATCCGCGTTTCATGGGAAGAAGCCTATTCCTGTTTTCGCCAAACCGTATTAAGTGTACTGAAATCATATCGCTAA

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14443.79 Da        Isoelectric Point: 11.0325

>AT113866 WP_033576632.1 NZ_CP033622:c1516798-1516403 [Dickeya zeae]
MTIKARIQSRLKRSKRYVFTRDDFKDLAGYDQVGRALRELVKEGQLLKVGYGVYTKARKNVITGRLMPASPGGSAAVVIE
ALERLKVDYRLADAASAYNSGKSTQVPASIEIKTPPRFKRVLSVGNSKLNG

Download         Length: 396 bp

>AT113866 NZ_CP033622:c1516798-1516403 [Dickeya zeae]
ATGACCATAAAAGCTCGTATTCAGTCGCGGCTGAAACGCTCGAAGCGTTATGTTTTCACTCGTGACGACTTCAAAGATCT
TGCTGGCTACGATCAAGTTGGCAGAGCGCTGCGTGAATTGGTAAAAGAAGGCCAACTGCTGAAAGTCGGTTATGGCGTCT
ATACCAAAGCGCGGAAAAATGTGATTACGGGTAGGCTAATGCCCGCCTCTCCCGGCGGCTCTGCTGCGGTGGTGATCGAA
GCGCTGGAGCGCCTGAAAGTGGACTATCGCCTGGCTGATGCAGCAAGCGCTTACAATAGCGGCAAGTCAACTCAGGTTCC
GGCGTCAATCGAAATCAAAACACCCCCACGTTTTAAGCGCGTGTTGTCAGTAGGGAATAGCAAGTTAAATGGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References