Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2430509..2430780 Replicon chromosome
Accession NZ_CP033605
Organism Escherichia coli O157:H7 strain TR01

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2430547..2430650 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2430509..2430780 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEL45_RS12535 2427666..2429105 + 1440 WP_123178863.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EEL45_RS12540 2429223..2429459 + 237 WP_085453913.1 DUF1480 family protein -
EEL45_RS12545 2429564..2429755 + 192 WP_001313035.1 YebW family protein -
EEL45_RS12550 2429756..2430412 - 657 WP_123178401.1 protein-serine/threonine phosphatase -
- 2430509..2430780 + 272 - - Antitoxin
- 2430547..2430650 - 104 - - Toxin
EEL45_RS12555 2430808..2431149 - 342 WP_000976472.1 YebY family protein -
EEL45_RS12560 2431161..2432033 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
EEL45_RS12565 2432037..2432411 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EEL45_RS12570 2432550..2432780 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EEL45_RS12575 2432882..2433538 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EEL45_RS12580 2433562..2434224 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T113843 NZ_CP033605:c2430650-2430547 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT113843 NZ_CP033605:2430509-2430780 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References