Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel2-ATphRel2/DUF4065(antitoxin)
Location 3111945..3113404 Replicon chromosome
Accession NZ_CP033576
Organism Bacillus velezensis strain NY12-2

Toxin (Protein)


Gene name phRel2 Uniprot ID -
Locus tag EEB07_RS16090 Protein ID WP_025649606.1
Coordinates 3111945..3112652 (+) Length 236 a.a.

Antitoxin (Protein)


Gene name ATphRel2 Uniprot ID -
Locus tag EEB07_RS16095 Protein ID WP_025649607.1
Coordinates 3112655..3113404 (+) Length 250 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEB07_RS20560 3107121..3107264 + 144 WP_164461507.1 hypothetical protein -
EEB07_RS16060 3107738..3108094 - 357 WP_050586581.1 hypothetical protein -
EEB07_RS16065 3108460..3108759 - 300 WP_014417475.1 hypothetical protein -
EEB07_RS16070 3108812..3109120 - 309 WP_017417555.1 hypothetical protein -
EEB07_RS16075 3109154..3109546 - 393 WP_123117738.1 hypothetical protein -
EEB07_RS16080 3109558..3111336 - 1779 WP_025649605.1 ribonuclease YeeF family protein -
EEB07_RS16090 3111945..3112652 + 708 WP_025649606.1 hypothetical protein Toxin
EEB07_RS16095 3112655..3113404 + 750 WP_025649607.1 DUF4065 domain-containing protein Antitoxin
EEB07_RS16100 3113434..3113618 - 185 Protein_3049 hypothetical protein -
EEB07_RS16105 3114150..3114485 - 336 WP_025649608.1 hypothetical protein -
EEB07_RS16110 3114507..3114683 - 177 Protein_3051 EndoU domain-containing protein -
EEB07_RS16115 3115409..3116152 + 744 WP_017417557.1 alpha/beta hydrolase -
EEB07_RS16120 3116496..3116828 + 333 WP_014417482.1 HIT domain-containing protein -
EEB07_RS16125 3116906..3117376 + 471 WP_014417483.1 hypothetical protein -
EEB07_RS16130 3117979..3118341 + 363 WP_123117739.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3090089..3114485 24396


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(113-224)


Sequences

Toxin        


Download         Length: 236 a.a.        Molecular weight: 28356.32 Da        Isoelectric Point: 6.6512

>T113822 WP_025649606.1 NZ_CP033576:3111945-3112652 [Bacillus velezensis]
VINCTCEMESFCDTFYELIIDINNAHKEISTEFHLEKKDDLINLKRKQINHVTHINEENTFSVDSLFLQLISNYREELLL
YSAYTDLQNKYKELILRLRTKETTSIVNKLKYYLVGKKEEGKIPINKCLNDLLGFRIHPTFFDHNKNCFQKTCQQLKQIY
NNRIDFMDSSKGDYKAFHIYLYGEEWKYFPWEIQIWCLKDRTQNDLSHKDHKQEHKKWAEIYKNSTEIELEMEGV

Download         Length: 708 bp

>T113822 NZ_CP033576:3111945-3112652 [Bacillus velezensis]
GTGATTAATTGTACATGTGAAATGGAATCATTCTGTGATACCTTTTATGAATTAATTATTGATATTAATAATGCGCATAA
AGAAATTTCAACTGAATTTCATCTAGAAAAGAAAGATGATCTAATAAATTTAAAAAGAAAACAAATTAATCATGTTACTC
ATATTAATGAGGAGAATACTTTTTCAGTCGATAGTTTATTCTTGCAGTTAATTTCTAATTACAGGGAGGAATTACTTCTT
TACAGTGCATATACTGATTTGCAGAATAAATACAAAGAATTAATTCTAAGGTTAAGGACGAAAGAAACTACTTCGATTGT
TAACAAACTTAAGTATTATCTTGTTGGCAAAAAGGAAGAGGGGAAAATCCCGATAAATAAATGTTTAAATGATTTATTAG
GATTTAGAATACACCCAACGTTTTTTGATCATAATAAGAACTGTTTTCAAAAAACATGTCAACAACTAAAACAGATTTAT
AATAATCGAATTGATTTCATGGATTCTTCGAAAGGCGATTATAAAGCTTTTCATATTTATTTATACGGCGAGGAATGGAA
ATACTTTCCTTGGGAAATACAAATCTGGTGTTTAAAAGATCGAACACAAAATGATTTGTCACATAAAGATCACAAACAAG
AACATAAAAAGTGGGCTGAAATTTACAAAAATTCAACGGAAATTGAACTGGAAATGGAAGGTGTTTAG

Antitoxin


Download         Length: 250 a.a.        Molecular weight: 29000.91 Da        Isoelectric Point: 5.5381

>AT113822 WP_025649607.1 NZ_CP033576:3112655-3113404 [Bacillus velezensis]
MAFHFIAIVSDFSGGRRYGWHYSSEDQLDKEYIKLFITRIKKECGHVQFGIHKLTTDDISWDSVVQMDSFFDDVIITNRI
DDFIEVVSNDQQLSAYDVAKFVLAIYPVSHLKLQKLLYYIYSEFLLRTGSKLFKDPIVAFKYGPVVEDVFHRYRIHGSSE
IDYKEDETFLLRTQEVAYTPSLIKIWTSEYGTAALQCIKDTLLKYGELDAFHLVDKTHQEGGPWARAYKPGQNCEITDDL
IIQYHQYAT

Download         Length: 750 bp

>AT113822 NZ_CP033576:3112655-3113404 [Bacillus velezensis]
ATGGCTTTTCATTTTATTGCAATCGTAAGTGATTTCTCTGGCGGAAGAAGATACGGTTGGCATTATTCGAGTGAAGACCA
GCTTGATAAAGAATATATCAAGTTATTTATAACTAGGATAAAAAAAGAATGTGGACATGTGCAATTCGGAATTCATAAGT
TAACAACAGACGATATCTCTTGGGATTCGGTAGTACAAATGGACTCTTTCTTTGATGATGTTATAATTACAAATCGAATT
GATGATTTTATAGAAGTTGTGTCAAACGATCAACAACTTTCTGCTTATGATGTTGCTAAATTCGTACTTGCCATTTATCC
TGTATCACATTTGAAATTACAAAAATTACTTTACTATATTTACTCTGAATTCTTACTTAGAACTGGATCAAAGTTATTTA
AAGATCCAATCGTTGCCTTTAAATATGGTCCTGTGGTCGAAGACGTATTTCATAGGTATAGAATACACGGAAGCTCTGAA
ATTGATTATAAAGAAGACGAAACGTTTTTACTCAGAACTCAAGAGGTTGCATACACGCCCTCTCTAATAAAAATCTGGAC
TTCTGAGTATGGAACAGCTGCTTTGCAATGCATAAAAGATACTCTGTTAAAGTATGGTGAATTAGATGCTTTTCATTTAG
TTGACAAGACTCATCAGGAAGGTGGACCATGGGCTAGAGCTTACAAGCCTGGCCAAAATTGTGAGATTACAGATGATCTG
ATTATTCAATATCATCAATATGCAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References