113820

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA(toxin)
Location 4737011..4738800 Replicon chromosome
Accession NZ_CP033575
Organism Shewanella algae strain KC-Na-R1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag EEY24_RS22400 Protein ID WP_123117053.1
Coordinates 4737463..4738800 (-) Length 446 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag EEY24_RS22395 Protein ID WP_123117052.1
Coordinates 4737011..4737466 (-) Length 152 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEY24_RS22380 4734435..4734710 - 276 WP_206192030.1 hypothetical protein -
EEY24_RS22385 4734918..4735436 - 519 WP_123117050.1 ankyrin repeat domain-containing protein -
EEY24_RS22390 4735442..4736650 - 1209 WP_164489490.1 HNH/ENDO VII family nuclease -
EEY24_RS22395 4737011..4737466 - 456 WP_123117052.1 helix-turn-helix domain-containing protein Antitoxin
EEY24_RS22400 4737463..4738800 - 1338 WP_123117053.1 type II toxin-antitoxin system HipA family toxin Toxin
EEY24_RS22405 4738961..4740172 - 1212 WP_107005245.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(163-392)

Antitoxin

Cro/C1-type helix-turn-helix domain

(86-141)


Sequences

Toxin        


Download         Length: 446 a.a.        Molecular weight: 50745.42 Da        Isoelectric Point: 4.7656

>T113820 WP_123117053.1 NZ_CP033575:c4738800-4737463 [Shewanella algae]
MEHLTIQAFINSQWIDIAKLSFPNSEQGHYRLTSLDYEQDYALAELNKDDMHAVSINHPVSLFFDEPGWLCFLDDIMPSG
ASRRYWLKYLDIADLSLDEQNFILLKFGTIAPVGNLRVKESLPERSVIADRLTFTVDDVKNRAADFLDYAQYRGAAAGGA
TGAGGEAPKLLLRCDDEQNIWIDSYQDDQQNRDLHYLVKYPRGSRSPVDCDILRAEYHYYHELAEMGFETIPTANMRLEE
GHSYPSLWLPRFDIYFNELGQQRYAMESVYSILGKAAGVTLDHEQTIRTLVHKITHSHMVLEQGYRFDIQAFVLDWVQRD
LLNILFGNSDNHGRNTAFLKGDGWIKLAPIYDFAPMKADPEGVARTTKWQAPLEVGGEYDFQGIADSLADLVPAQELMAA
LKFSAQQCLNLKQRLIARGVPERIIDMPAIGFTYIEDKLTRWGLV

Download         Length: 1338 bp

>T113820 NZ_CP033575:c4738800-4737463 [Shewanella algae]
ATGGAACATTTAACCATTCAGGCTTTTATCAATAGCCAATGGATAGATATTGCAAAGCTCTCTTTTCCAAACAGCGAACA
AGGTCATTATCGGCTTACTTCATTAGATTACGAGCAAGATTATGCCCTGGCAGAGCTCAATAAAGACGACATGCATGCCG
TTTCGATAAACCACCCTGTCAGCCTGTTTTTTGATGAGCCGGGGTGGCTTTGTTTCCTCGATGACATCATGCCTAGCGGT
GCAAGTCGCCGCTACTGGCTTAAGTATCTCGATATCGCAGATCTGAGCTTAGATGAGCAAAATTTTATCCTGTTAAAGTT
TGGCACTATCGCGCCGGTAGGTAATTTACGGGTCAAGGAATCATTGCCTGAGCGCTCAGTCATTGCTGACAGGCTGACAT
TCACCGTGGATGACGTTAAAAATCGCGCGGCTGATTTTCTGGATTACGCACAATACCGAGGCGCTGCTGCTGGTGGTGCA
ACAGGAGCTGGCGGGGAAGCGCCCAAGTTGCTGTTACGTTGTGACGATGAGCAAAACATCTGGATTGATAGCTATCAGGA
CGACCAACAAAACCGAGACCTGCATTATTTGGTGAAATACCCAAGAGGCTCACGTTCACCCGTTGATTGTGACATCTTGC
GAGCAGAGTACCACTATTACCACGAGCTGGCAGAAATGGGCTTTGAGACTATTCCAACGGCCAATATGCGACTCGAGGAG
GGGCATTCCTACCCATCATTGTGGCTGCCGCGTTTTGATATTTATTTCAATGAACTCGGCCAGCAGCGTTACGCGATGGA
ATCGGTTTACTCGATACTGGGTAAAGCTGCCGGAGTTACCTTAGATCATGAGCAAACCATAAGAACGCTCGTCCACAAGA
TCACTCATAGCCATATGGTCTTAGAGCAAGGTTATCGGTTTGATATTCAGGCTTTTGTGCTTGACTGGGTTCAGAGAGAC
TTACTCAATATCCTATTTGGTAACAGCGATAACCACGGGCGTAATACCGCATTTCTTAAAGGTGATGGTTGGATAAAGCT
TGCCCCTATCTATGACTTTGCACCAATGAAGGCTGATCCTGAAGGGGTGGCCAGAACCACAAAGTGGCAAGCACCGCTCG
AAGTTGGGGGTGAGTATGACTTTCAAGGTATTGCCGATTCGTTGGCCGATTTGGTGCCTGCTCAAGAGTTAATGGCAGCA
TTAAAGTTCTCCGCCCAGCAATGTCTTAACTTGAAGCAGCGCTTAATTGCGCGTGGTGTACCGGAACGGATTATCGATAT
GCCTGCGATTGGCTTTACTTATATCGAAGACAAGCTAACAAGGTGGGGATTGGTATGA

Antitoxin


Download         Length: 152 a.a.        Molecular weight: 16699.96 Da        Isoelectric Point: 10.5046

>AT113820 WP_123117052.1 NZ_CP033575:c4737466-4737011 [Shewanella algae]
MSDKTSTLESAKEAIARLRANRRQAGDVAIEASQYQLSLDAEETHAKQAPPPQRASKHSGRVSTVERRKAIEGVTQRLLR
GELTQGQALKTLRIEVLGLTQDEYSNLAKVSRKTLSDVENDRGSYKTDILDRLFKPFGLRVGIVPISTGIK

Download         Length: 456 bp

>AT113820 NZ_CP033575:c4737466-4737011 [Shewanella algae]
ATGAGTGATAAAACATCTACCCTTGAGTCTGCTAAAGAGGCTATTGCTCGTCTTAGAGCTAATCGTCGGCAAGCTGGTGA
TGTTGCAATTGAAGCGTCACAATATCAGCTCTCACTAGACGCTGAAGAGACTCACGCAAAGCAAGCCCCCCCCCCTCAAC
GTGCTTCCAAGCATAGCGGGAGGGTGAGTACTGTTGAGAGACGTAAGGCCATCGAAGGCGTTACCCAAAGGCTATTACGC
GGAGAACTTACTCAAGGGCAAGCTCTTAAAACTTTACGTATTGAGGTTTTAGGCCTAACCCAAGACGAGTATTCAAATTT
GGCTAAAGTGTCACGTAAGACCCTCTCTGACGTTGAGAACGATCGGGGGAGCTATAAGACTGATATTCTCGACCGATTGT
TTAAACCCTTTGGCCTGAGAGTGGGGATTGTGCCTATCTCTACCGGCATCAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References