Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /Xre(antitoxin) |
| Location | 1406909..1408054 | Replicon | chromosome |
| Accession | NZ_CP033575 | ||
| Organism | Shewanella algae strain KC-Na-R1 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | EEY24_RS07425 | Protein ID | WP_054744620.1 |
| Coordinates | 1407308..1408054 (+) | Length | 249 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A7X5Z3H2 |
| Locus tag | EEY24_RS07420 | Protein ID | WP_025011540.1 |
| Coordinates | 1406909..1407271 (+) | Length | 121 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EEY24_RS07405 | 1404373..1405110 | - | 738 | WP_123115805.1 | thioredoxin domain-containing protein | - |
| EEY24_RS07410 | 1405251..1405892 | - | 642 | WP_123117173.1 | DnaJ domain-containing protein | - |
| EEY24_RS07415 | 1406023..1406676 | - | 654 | WP_025886967.1 | oxygen-insensitive NAD(P)H-dependent nitroreductase NfsB | - |
| EEY24_RS07420 | 1406909..1407271 | + | 363 | WP_025011540.1 | MbcA/ParS/Xre antitoxin family protein | Antitoxin |
| EEY24_RS07425 | 1407308..1408054 | + | 747 | WP_054744620.1 | RES family NAD+ phosphorylase | Toxin |
| EEY24_RS07430 | 1408068..1409633 | - | 1566 | WP_044733835.1 | hypothetical protein | - |
| EEY24_RS07435 | 1409732..1410457 | - | 726 | WP_025886969.1 | amino acid ABC transporter ATP-binding protein | - |
| EEY24_RS07440 | 1410450..1411127 | - | 678 | WP_025011537.1 | amino acid ABC transporter permease | - |
| EEY24_RS07445 | 1411134..1411859 | - | 726 | WP_044735676.1 | basic amino acid ABC transporter substrate-binding protein | - |
| EEY24_RS07450 | 1412271..1412837 | + | 567 | WP_025011535.1 | hypoxanthine phosphoribosyltransferase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 28870.61 Da Isoelectric Point: 4.6112
>T113817 WP_054744620.1 NZ_CP033575:1407308-1408054 [Shewanella algae]
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
MDFSALEPQDFFPRPYLGRGYRLVESQEEAATLSLVDDFDEQMLLESLLDEVKPPYRSGTEHLHYLLKTPFRYPPLRHGS
RFGSITMESFFYASESWQTCLAEVAYYRFVFMADMLEPYLEPLRSEHMLYSVDINARDCADLTLLQGQEVQQQLTHKSNY
TYTQAMGAWLLQQQAQMIRYTSARAEEGVNLALHDPLVLQSTEPQECEYWICQSSADKVAFSRRNSRSMPLTWFLKDFLQ
DGQLPRPA
Download Length: 747 bp
>T113817 NZ_CP033575:1407308-1408054 [Shewanella algae]
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCAGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTAGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGACAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGTGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAACCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCCGCCTGA
ATGGATTTTAGCGCGTTAGAGCCGCAGGACTTTTTCCCTCGCCCTTACCTTGGCCGCGGTTATCGCCTGGTCGAGTCCCA
GGAAGAAGCAGCCACCCTGAGCCTGGTGGATGATTTTGACGAACAGATGCTGCTTGAGTCTCTGCTCGATGAGGTTAAAC
CGCCTTACCGAAGTGGAACAGAGCACTTGCATTATCTGCTCAAGACCCCGTTTCGTTATCCGCCGCTGCGCCATGGCTCG
CGCTTTGGCAGTATCACAATGGAAAGCTTCTTTTATGCCAGTGAATCCTGGCAGACCTGTTTGGCCGAAGTAGCTTACTA
TCGTTTTGTCTTTATGGCCGACATGCTGGAGCCTTATCTGGAGCCGCTGCGCTCTGAGCATATGCTGTACTCTGTGGATA
TCAATGCCCGCGATTGTGCCGACCTGACGCTATTGCAGGGACAGGAAGTGCAGCAGCAACTGACTCACAAGTCGAACTAT
ACCTATACCCAGGCTATGGGTGCCTGGCTGCTGCAACAGCAGGCGCAGATGATCCGCTACACTTCGGCCAGAGCCGAAGA
GGGCGTTAACCTGGCGCTGCACGATCCTTTGGTGTTGCAATCAACCGAGCCGCAGGAGTGTGAATACTGGATCTGCCAAA
GCTCGGCCGACAAGGTGGCTTTCAGTCGTCGTAATAGCCGCAGCATGCCATTGACCTGGTTTTTAAAAGACTTTTTGCAG
GACGGGCAGTTGCCGCGTCCCGCCTGA
Antitoxin
Download Length: 121 a.a. Molecular weight: 13125.14 Da Isoelectric Point: 10.4675
>AT113817 WP_025011540.1 NZ_CP033575:1406909-1407271 [Shewanella algae]
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
MNTLEKANAAEVLFKAFSNACSELQLTQAEASRIIGVNPSTLSRNSGKGFKPDSKQGELQLQLIRLYRSLYAIAGGEKAF
MRHWLNSPNKALNGTPKTLLQTVVGLVSVNQYLDAMRGKV
Download Length: 363 bp
>AT113817 NZ_CP033575:1406909-1407271 [Shewanella algae]
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAGAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
ATGAATACCCTAGAGAAAGCCAATGCAGCCGAGGTATTATTCAAGGCGTTTTCCAATGCTTGCAGCGAGTTACAACTTAC
CCAGGCCGAGGCCAGCCGTATCATAGGTGTTAATCCCAGCACCTTGAGCCGTAACAGCGGCAAGGGGTTTAAACCCGATT
CCAAGCAGGGGGAACTGCAGTTGCAGCTTATCCGCCTGTATCGCTCGTTGTATGCCATAGCGGGTGGTGAGAAAGCCTTT
ATGCGTCACTGGCTCAACAGCCCCAACAAGGCGCTGAATGGGACCCCCAAGACTTTATTGCAAACCGTGGTTGGCCTGGT
GAGTGTTAACCAATATCTGGATGCGATGCGAGGCAAGGTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|