Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 1088792..1090335 Replicon chromosome
Accession NZ_CP033575
Organism Shewanella algae strain KC-Na-R1

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag EEY24_RS06090 Protein ID WP_123115694.1
Coordinates 1088792..1090087 (-) Length 432 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag EEY24_RS06095 Protein ID WP_025011264.1
Coordinates 1090087..1090335 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEY24_RS06075 1084292..1084876 + 585 WP_123115692.1 LysE family translocator -
EEY24_RS06080 1084954..1086981 - 2028 WP_028781109.1 S9 family peptidase -
EEY24_RS06085 1087285..1088652 + 1368 WP_123115693.1 L-cystine transporter -
EEY24_RS06090 1088792..1090087 - 1296 WP_123115694.1 type II toxin-antitoxin system HipA family toxin Toxin
EEY24_RS06095 1090087..1090335 - 249 WP_025011264.1 type II toxin-antitoxin system antitoxin HipB Antitoxin
EEY24_RS06100 1090848..1092539 + 1692 WP_123115695.1 ATP-binding cassette domain-containing protein -
EEY24_RS06105 1092552..1092926 - 375 WP_014386412.1 PH domain-containing protein -
EEY24_RS06110 1092937..1094862 - 1926 WP_123115696.1 U32 family peptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA-like, C-terminal

(149-399)

Antitoxin

Cro/C1-type helix-turn-helix domain

(15-64)


Sequences

Toxin        


Download         Length: 432 a.a.        Molecular weight: 48429.13 Da        Isoelectric Point: 9.3227

>T113816 WP_123115694.1 NZ_CP033575:c1090087-1088792 [Shewanella algae]
MQKLIAYMNGELVGTLAKHKNGAHTFQYDKDWITNAMARPLSLSLRLQLPPITSDAVINYFDNLLPDSPQVRDRIVARYK
ASSKQPFDLLKEVGKDSVGAIALFPPEHPYKKEPLSYEILDNKKLEAVLSAYKSDIPLGMLKEEEDFRISVAGAQEKTAL
LFIDGQWCIPKGNTPTTHIIKLPIGEIPQANSTLDLKDSVENEYLCIELAKALGFAVPSVNIIKTDNLKALAVERFDRRW
TKDRAGLLRLPQEDICQVFGMPSSIKYESQGGPGIEQIMKLLMGSSNALEDRYNFMRFQVFQWIIGATDGHAKNFSIYID
KGGSYRLTPFYDILSAYPLLGGLNIRQLKLAMGLKATKGKKYEINKILPRHFLDTAKAVNFSQDKMQRIMDEMKGALPEA
ISQVRANLPEGFPENISNSIFENAKKTIKKI

Download         Length: 1296 bp

>T113816 NZ_CP033575:c1090087-1088792 [Shewanella algae]
ATGCAAAAGCTAATAGCATACATGAATGGTGAACTTGTTGGCACCTTGGCGAAGCATAAGAACGGCGCTCACACTTTTCA
ATATGATAAGGACTGGATAACCAATGCAATGGCTCGCCCACTGTCATTGTCTTTGAGGCTTCAATTACCACCTATCACTT
CCGATGCTGTTATCAACTATTTTGACAACCTCTTACCAGACAGCCCACAAGTCAGAGATAGGATCGTTGCAAGGTACAAA
GCCTCATCCAAACAACCATTTGATCTCTTGAAAGAAGTTGGAAAGGATAGTGTTGGTGCTATTGCACTATTTCCTCCCGA
ACACCCCTATAAAAAAGAGCCACTCAGCTACGAAATATTGGATAACAAGAAACTAGAAGCGGTTCTTTCTGCATACAAGT
CTGATATTCCCCTCGGGATGCTCAAAGAGGAAGAAGACTTTAGGATCTCAGTAGCAGGTGCTCAAGAAAAAACCGCACTC
TTATTCATTGATGGACAATGGTGTATACCGAAAGGAAACACCCCAACTACTCACATTATCAAGCTACCAATAGGCGAAAT
ACCACAAGCTAACTCGACACTGGATCTCAAAGATAGCGTAGAAAATGAATATCTTTGCATTGAGCTAGCTAAAGCGCTGG
GATTCGCAGTTCCCAGCGTCAATATAATCAAAACAGACAACCTTAAAGCTTTAGCTGTAGAACGATTTGATCGACGCTGG
ACAAAAGACAGAGCAGGCTTGCTACGCTTACCTCAAGAAGATATTTGCCAAGTGTTTGGTATGCCATCATCCATCAAATA
TGAATCTCAAGGTGGTCCAGGCATAGAACAGATCATGAAGTTATTAATGGGCTCAAGTAATGCACTTGAAGATCGATATA
ACTTCATGAGATTCCAGGTATTTCAATGGATCATTGGGGCTACGGATGGACATGCTAAAAACTTTTCTATCTATATTGAT
AAAGGAGGTAGCTATCGACTCACTCCATTCTACGACATTCTGTCGGCCTACCCATTACTGGGAGGACTCAATATTAGACA
ACTTAAGCTCGCTATGGGATTAAAAGCCACAAAAGGCAAGAAGTATGAAATCAATAAAATCCTGCCTCGTCACTTTTTAG
ATACTGCTAAAGCTGTGAATTTTAGTCAGGATAAGATGCAAAGAATAATGGATGAAATGAAAGGTGCGTTACCTGAGGCA
ATCTCGCAAGTAAGGGCGAATCTACCCGAGGGCTTTCCAGAGAATATCTCCAACTCTATTTTTGAGAATGCCAAGAAAAC
AATTAAAAAAATCTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9366.70 Da        Isoelectric Point: 6.2564

>AT113816 WP_025011264.1 NZ_CP033575:c1090335-1090087 [Shewanella algae]
MIYSPKQLADMMLLIRQKNGWTQSELAKKVGIKQATISNFENNPNKTTLSTFFKLVQAMDLTLSIQEKTQLTSPSENDDE
SW

Download         Length: 249 bp

>AT113816 NZ_CP033575:c1090335-1090087 [Shewanella algae]
ATGATATATAGTCCAAAGCAACTCGCAGATATGATGCTACTGATACGCCAAAAGAATGGCTGGACTCAGTCAGAGTTGGC
GAAAAAAGTCGGTATAAAGCAAGCAACAATCTCGAACTTCGAGAACAACCCCAACAAAACAACGCTTTCTACCTTCTTTA
AGCTTGTACAAGCGATGGATCTAACACTGAGTATCCAAGAAAAAACACAGCTGACTTCGCCAAGTGAAAATGATGATGAG
AGTTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References