Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 154577..154811 Replicon chromosome
Accession NZ_CP033510
Organism Shigella flexneri strain 2016AM-0877

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 154578..154681 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 154577..154811 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEL47_RS00745 150023..150490 - 468 Protein_146 DNA-binding transcriptional regulator PgrR -
EEL47_RS00750 150554..150864 + 311 Protein_147 transposase -
EEL47_RS00755 150907..152102 - 1196 Protein_148 IS3 family transposase -
EEL47_RS00760 152157..153005 + 849 Protein_149 IS3-like element IS600 family transposase -
EEL47_RS00765 153122..153403 + 282 WP_005127484.1 excisionase -
EEL47_RS26040 153369..154446 + 1078 Protein_151 phage integrase Arm DNA-binding domain-containing protein -
- 154577..154811 + 235 - - Antitoxin
- 154578..154681 - 104 - - Toxin
EEL47_RS00785 154839..155180 - 342 WP_000976476.1 YebY family protein -
EEL47_RS00790 155193..156065 - 873 Protein_153 copper homeostasis membrane protein CopD -
EEL47_RS00795 156069..156443 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EEL47_RS00800 156582..156812 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EEL47_RS00805 156914..157570 + 657 Protein_156 carbon-nitrogen hydrolase family protein -
EEL47_RS00810 157594..158256 + 663 WP_000944268.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T113767 NZ_CP033510:c154681-154578 [Shigella flexneri]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT113767 NZ_CP033510:154577-154811 [Shigella flexneri]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGCTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References