Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4673213..4673680 Replicon chromosome
Accession NZ_CP033504
Organism Serratia sp. LS-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EDY99_RS22265 Protein ID WP_116286573.1
Coordinates 4673444..4673680 (+) Length 79 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EDY99_RS22260 Protein ID WP_033645226.1
Coordinates 4673213..4673410 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EDY99_RS22230 4668403..4669671 + 1269 WP_089195354.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
EDY99_RS22235 4669668..4670867 + 1200 WP_033645005.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
EDY99_RS22240 4670903..4671466 - 564 WP_060438278.1 DcrB family lipoprotein -
EDY99_RS22245 4671547..4671981 - 435 WP_123062069.1 GNAT family N-acetyltransferase -
EDY99_RS22250 4672023..4672682 - 660 WP_025304889.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
EDY99_RS22255 4672903..4673148 + 246 WP_025304890.1 sulfurtransferase TusA -
EDY99_RS22260 4673213..4673410 + 198 WP_033645226.1 hypothetical protein Antitoxin
EDY99_RS22265 4673444..4673680 + 237 WP_116286573.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EDY99_RS22270 4673740..4676058 - 2319 WP_123062070.1 zinc/cadmium/mercury/lead-transporting ATPase -
EDY99_RS22275 4676739..4678202 + 1464 WP_033644999.1 serralysin family metalloprotease -
EDY99_RS22280 4678257..4678634 + 378 WP_025304893.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-73)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 79 a.a.        Molecular weight: 9114.80 Da        Isoelectric Point: 11.3259

>T113763 WP_116286573.1 NZ_CP033504:4673444-4673680 [Serratia sp. LS-1]
MAEIVGFIANDNPLAARKMKVLIMEAVTPAARHPRIFRRGRVDGTHEIPLHPHYLLIYQVLETHIRVLRVLHTRRQYP

Download         Length: 237 bp

>T113763 NZ_CP033504:4673444-4673680 [Serratia sp. LS-1]
CTGGCGGAGATTGTGGGATTCATCGCCAACGATAACCCTCTGGCGGCCAGAAAAATGAAGGTTCTCATCATGGAGGCCGT
CACTCCCGCCGCCAGGCATCCCCGAATTTTCCGGCGTGGCAGAGTGGACGGCACGCATGAAATCCCCTTGCATCCCCATT
ATCTCCTGATTTACCAGGTGCTGGAAACTCACATCCGGGTGTTGCGGGTATTACATACGCGCCGACAATATCCTTAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7395.40 Da        Isoelectric Point: 4.1359

>AT113763 WP_033645226.1 NZ_CP033504:4673213-4673410 [Serratia sp. LS-1]
MSILLLPTVAKMENEEHTQGYERWFLERVQEAMDEPWPGIPHDDVMAEMDAVIAAAEARINAKQA

Download         Length: 198 bp

>AT113763 NZ_CP033504:4673213-4673410 [Serratia sp. LS-1]
ATGAGTATTTTACTACTGCCTACGGTTGCCAAGATGGAAAATGAGGAACACACACAGGGCTATGAGCGCTGGTTTCTTGA
AAGAGTTCAGGAAGCCATGGATGAGCCGTGGCCCGGTATTCCTCATGATGACGTGATGGCTGAAATGGATGCTGTTATCG
CTGCTGCAGAAGCCAGGATCAACGCGAAGCAGGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References