Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 2054209..2054721 Replicon chromosome
Accession NZ_CP033460
Organism Staphylococcus debuckii strain SDB 2975

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag CNQ82_RS09850 Protein ID WP_123145113.1
Coordinates 2054209..2054415 (-) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag CNQ82_RS09855 Protein ID WP_095104322.1
Coordinates 2054428..2054721 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CNQ82_RS09835 2050137..2051354 + 1218 WP_123145110.1 rod shape-determining protein RodA -
CNQ82_RS13170 2051426..2051566 - 141 WP_095104330.1 hypothetical protein -
CNQ82_RS09840 2051642..2053840 - 2199 WP_123145111.1 heavy metal translocating P-type ATPase -
CNQ82_RS09845 2053985..2054194 - 210 WP_123145112.1 copper ion binding protein -
CNQ82_RS09850 2054209..2054415 - 207 WP_123145113.1 cation transporter Toxin
CNQ82_RS09855 2054428..2054721 - 294 WP_095104322.1 copper-sensing transcriptional repressor CsoR Antitoxin
CNQ82_RS09860 2054885..2056366 + 1482 WP_123145114.1 cardiolipin synthase -
CNQ82_RS09865 2056430..2057038 + 609 WP_123145671.1 HD domain-containing protein -
CNQ82_RS09870 2057107..2057619 - 513 WP_123145115.1 GNAT family N-acetyltransferase -
CNQ82_RS09875 2057734..2058609 - 876 WP_123145116.1 membrane protein insertase YidC -
CNQ82_RS09880 2058699..2059337 - 639 WP_123145117.1 thiamine phosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Heavy metal-associated domain, HMA

(24-65)

Antitoxin

Metal-sensitive transcriptional repressor

(3-95)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7746.63 Da        Isoelectric Point: 4.2088

>T113720 WP_123145113.1 NZ_CP033460:c2054415-2054209 [Staphylococcus debuckii]
MQTSIIKIDGLETEEAQHKLHQHLSEMTGVSAVQVDMDSNEIRISYETPVNLNNLEKEIYDAGYQILN

Download         Length: 207 bp

>T113720 NZ_CP033460:c2054415-2054209 [Staphylococcus debuckii]
ATGCAAACTAGTATTATAAAAATTGATGGTTTAGAAACTGAAGAAGCACAACATAAATTACACCAACATCTTAGCGAAAT
GACTGGTGTTTCTGCGGTACAAGTAGATATGGATTCCAACGAAATTCGTATTAGTTATGAAACACCTGTCAATTTAAATA
ATCTTGAAAAAGAAATTTATGATGCAGGTTATCAAATATTAAATTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11076.69 Da        Isoelectric Point: 6.4854

>AT113720 WP_095104322.1 NZ_CP033460:c2054721-2054428 [Staphylococcus debuckii]
MTENDKAHHSEQIKSNLKARLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVAVKLLDHHMKGCIMHKVDDGHA
EEAMEELLVTVQKLIKD

Download         Length: 294 bp

>AT113720 NZ_CP033460:c2054721-2054428 [Staphylococcus debuckii]
ATGACTGAAAATGACAAAGCGCATCATTCTGAACAAATTAAATCTAACTTAAAAGCACGTCTCAATCGAATTGAAGGTCA
AGTAAGAGCAATTAATCGGATGATTGATGAAGATGTTTATTGTGATGATGTACTCACGCAAATACGTGCTACACGCTCAG
CCTTAAATAGTGTGGCAGTTAAGCTGCTCGATCATCATATGAAAGGCTGTATTATGCATAAAGTAGATGACGGTCATGCA
GAGGAAGCGATGGAAGAATTATTAGTAACTGTACAAAAATTGATTAAAGATTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References