Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 1793101..1794788 Replicon chromosome
Accession NZ_CP033457
Organism Vibrio alginolyticus strain SNU_SP1

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag EEA47_RS08505 Protein ID WP_213905055.1
Coordinates 1793101..1794324 (-) Length 408 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag EEA47_RS08510 Protein ID WP_005378671.1
Coordinates 1794321..1794788 (-) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EEA47_RS08490 (EEA47_08800) 1788771..1789463 - 693 WP_005389693.1 ATPase -
EEA47_RS08495 (EEA47_08805) 1789523..1791358 - 1836 WP_005389692.1 TonB-dependent vitamin B12 receptor -
EEA47_RS08500 (EEA47_08810) 1791799..1792908 + 1110 WP_268206428.1 tRNA (uridine(54)-C5)-methyltransferase TrmA -
EEA47_RS08505 (EEA47_08815) 1793101..1794324 - 1224 WP_213905055.1 RelA/SpoT domain-containing protein Toxin
EEA47_RS08510 (EEA47_08820) 1794321..1794788 - 468 WP_005378671.1 DUF4065 domain-containing protein Antitoxin
EEA47_RS08515 (EEA47_08825) 1795117..1795788 - 672 WP_213905054.1 hypothetical protein -
EEA47_RS08520 (EEA47_08830) 1795933..1796949 + 1017 WP_250158403.1 hypothetical protein -
EEA47_RS08525 (EEA47_08835) 1797132..1797776 + 645 WP_213905052.1 inovirus Gp2 family protein -
EEA47_RS08530 (EEA47_08840) 1797817..1798263 - 447 WP_213905051.1 hypothetical protein -
EEA47_RS08535 (EEA47_08845) 1798374..1799363 - 990 WP_140089486.1 50S ribosome-binding GTPase -
EEA47_RS08540 (EEA47_08850) 1799441..1799650 + 210 WP_213905050.1 AlpA family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(111-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 408 a.a.        Molecular weight: 45865.61 Da        Isoelectric Point: 5.3831

>T113715 WP_213905055.1 NZ_CP033457:c1794324-1793101 [Vibrio alginolyticus]
VSNKENSVVSFYIDDTPTAEQASKTFQDDYELDFQDFIERTVNESAAEDFSYSNNGVKKAGRRLRKREGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIVDKLQRKSLDGETANATCVTNMNDIGGCRAIFPDLISLEKV
KSQLQLTVEKVGRVRIKDIDDYITSPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSSNEGKSSLQVQWEELLSIMSQYIADAEGAIELSDIDKADFSKRLVVLDREINALNRLSSFKILSEKVNSYCDSSI
EHVLLVINETSRELIFSEEFENYSQAISVYNAAEKVTRSYSRATSRLNTLLISTKNMGQLSEAYPNYLGDCASFITLLED
GMLSGES

Download         Length: 1224 bp

>T113715 NZ_CP033457:c1794324-1793101 [Vibrio alginolyticus]
GTGAGTAACAAAGAAAATAGTGTCGTCAGTTTTTACATTGACGACACCCCCACAGCTGAACAAGCTTCAAAAACCTTCCA
AGACGACTACGAACTGGACTTTCAAGATTTTATAGAAAGAACGGTAAATGAAAGTGCTGCTGAAGACTTCTCGTACTCAA
ATAATGGAGTAAAGAAAGCTGGAAGACGGCTTCGCAAGAGAGAGGGCGACCTCAAGTCAGCTACTGCTACAATCCAACAG
TTTCGAGCCGCACACGAAAAGCCATTAAACACTATCGCATATCTTGTTGGTCGCTGTTGCCGTGAGCTGGGTATAGATGT
TAAACCAGTTACACGGTTAAAGCGCTTAGAAACAATCGTAGATAAGTTGCAGCGTAAATCTCTTGATGGTGAAACGGCAA
ATGCTACTTGTGTAACCAATATGAATGATATTGGCGGCTGCAGGGCGATTTTTCCGGATTTAATTTCATTGGAGAAGGTG
AAATCTCAACTGCAACTTACAGTTGAGAAGGTAGGCCGAGTTAGAATTAAAGATATTGATGACTATATTACTAGTCCTAA
ACCTAATGATTGTGGTTACCGAAGCTTGCATGTGATTTATCGCTATGACCATGCTAGTGGTAAAAGTTTTAACATTGAGG
CTCAGCTACGTACTCGACTTCAACATCTTTGGGCTACTACAGTGGAAATTGTCGACATCCTAGAAGGTACCAAGATTAAG
ACTCACTCTCACAGTTCAAATGAAGGCAAGAGCAGTTTACAGGTTCAATGGGAAGAATTGCTTTCGATAATGAGCCAATA
CATTGCTGATGCTGAAGGGGCTATAGAGCTAAGTGATATCGATAAAGCAGACTTTTCAAAGCGTTTGGTCGTCTTGGACC
GCGAAATCAATGCGCTAAATCGCTTGAGTAGTTTTAAAATTTTATCTGAAAAGGTTAATTCTTACTGTGATAGTTCCATT
GAGCACGTATTGCTAGTTATTAACGAAACTTCACGAGAATTGATCTTTAGTGAAGAGTTTGAAAATTACAGCCAAGCAAT
TTCAGTTTATAACGCAGCTGAGAAAGTCACTCGTAGCTACTCACGAGCAACCTCGAGACTCAATACCCTTCTCATATCCA
CAAAAAATATGGGCCAACTTTCGGAAGCCTACCCTAACTATCTAGGCGATTGTGCCTCATTCATCACTCTGCTTGAAGAC
GGAATGCTGTCTGGTGAAAGTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17516.97 Da        Isoelectric Point: 7.9061

>AT113715 WP_005378671.1 NZ_CP033457:c1794788-1794321 [Vibrio alginolyticus]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDVALDQESESIVKDVVSKLGHLTGPQLVDLTHREGSPWHQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT113715 NZ_CP033457:c1794788-1794321 [Vibrio alginolyticus]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCTTGCTCAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCCAATTTGCAGCTACAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCACACTTCCAGCGTCCTCTCGTCGTAG
ATGATGTATTTGCTTGGAAGTTTGGTCCAGTGGTGCCATCTGTTTACTTTCGCTTTAAATCCTACGGTAGTAGTGTGATC
ACTGAACAATGTGATGTAGCACTAGACCAAGAAAGTGAGTCTATTGTTAAAGATGTAGTCTCTAAGCTGGGCCATTTGAC
GGGGCCTCAACTTGTAGATTTAACTCACCGCGAAGGAAGTCCATGGCATCAGGTATGGGATGGCACACACCAAAAAGTGA
TTCCGGACCATTTGATTCAAGCCCATTACACTCAAATCAAACAATCCGGACGAACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References