Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 365717..366318 Replicon chromosome
Accession NZ_CP033431
Organism Burkholderia gladioli strain Burkholderia gladioli Co14

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EDD84_RS21460 Protein ID WP_080757361.1
Coordinates 365717..366022 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EDD84_RS21465 Protein ID WP_036032828.1
Coordinates 366019..366318 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EDD84_RS21445 361269..361760 - 492 WP_025097476.1 MarR family transcriptional regulator -
EDD84_RS21450 362205..363629 + 1425 WP_123037338.1 methyltransferase regulatory domain-containing protein -
EDD84_RS21455 363733..365286 - 1554 WP_164465660.1 hypothetical protein -
EDD84_RS21460 365717..366022 + 306 WP_080757361.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EDD84_RS21465 366019..366318 + 300 WP_036032828.1 putative addiction module antidote protein Antitoxin
EDD84_RS21470 366423..367613 - 1191 WP_046576043.1 MFS transporter -
EDD84_RS21475 368261..369667 + 1407 WP_123037340.1 type III secretion protein -
EDD84_RS21480 369698..369943 + 246 WP_013689020.1 hypothetical protein -
EDD84_RS21485 370027..370398 + 372 WP_186051059.1 hypothetical protein -
EDD84_RS21490 370519..370974 + 456 WP_013689018.1 CesT family type III secretion system chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-83)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-92)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11299.10 Da        Isoelectric Point: 10.7436

>T113700 WP_080757361.1 NZ_CP033431:365717-366022 [Burkholderia gladioli]
MAEIITSDVFDRWLRELRDIRARARIEVRIRRLSLGNPGDVKPVGNGVSELRIDHGPGYRVYYMKRGRVVVILLCGGNKD
SQGHDIAVAKAIAAQWKGSTI

Download         Length: 306 bp

>T113700 NZ_CP033431:365717-366022 [Burkholderia gladioli]
ATGGCCGAAATCATCACGAGTGATGTATTCGACCGATGGCTCAGAGAACTTCGCGACATCCGTGCAAGAGCGCGGATCGA
AGTTCGCATTCGTCGCCTGAGCCTCGGCAACCCGGGTGACGTGAAGCCGGTTGGCAACGGTGTCTCGGAACTGCGAATCG
ACCATGGCCCTGGATATCGGGTCTACTACATGAAGCGAGGCCGCGTCGTGGTCATATTGCTATGCGGCGGCAATAAGGAT
AGTCAAGGCCATGACATTGCCGTCGCCAAGGCAATCGCTGCGCAATGGAAGGGGTCCACGATATGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10596.95 Da        Isoelectric Point: 4.7420

>AT113700 WP_036032828.1 NZ_CP033431:366019-366318 [Burkholderia gladioli]
MKAVKFSRYDTVDYLQTEEEIAAYLDAAVEDGDPALIAAALGDIARARNISQLARDTGMSREGIYRALSGDGNPSFATVM
KIANALGLRISFRPATSSP

Download         Length: 300 bp

>AT113700 NZ_CP033431:366019-366318 [Burkholderia gladioli]
ATGAAAGCCGTGAAGTTCAGTCGATACGATACCGTCGACTATCTGCAGACCGAGGAGGAGATTGCCGCCTACCTCGACGC
TGCGGTCGAAGACGGCGATCCGGCCTTGATCGCCGCAGCCCTTGGTGACATCGCGCGTGCGCGAAATATCAGCCAACTCG
CGCGCGACACCGGCATGAGTCGTGAAGGCATTTATCGGGCCCTGTCGGGCGACGGCAATCCGAGTTTTGCTACCGTGATG
AAAATTGCGAATGCGCTTGGGCTACGGATATCCTTTCGACCCGCGACATCGAGCCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References