Detailed information of TA system TA113695

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 60439..61394
• Replicon: plasmid p1
• Accession: NZ_CP033429
• Organism: Burkholderia gladioli strain Burkholderia gladioli Co14

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: EDD84_RS00370
• Protein ID: WP_123035900.1
• Coordinates: 60439..60972 (-)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: EDD84_RS00375
• Protein ID: WP_123035901.1
• Coordinates: 60969..61394 (-)
• Length: 142 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EDD84_RS00340	56323..58152	-	1830	WP_123035896.1	site-specific integrase	-
EDD84_RS00345	58516..58959	-	444	WP_123035897.1	hypothetical protein	-
EDD84_RS00350	58956..59198	-	243	WP_123035898.1	hypothetical protein	-
EDD84_RS00355	59213..59497	-	285	WP_017917860.1	hypothetical protein	-
EDD84_RS00360	59573..59794	-	222	WP_123035899.1	hypothetical protein	-
EDD84_RS00370	60439..60972	-	534	WP_123035900.1	RES family NAD+ phosphorylase	Toxin
EDD84_RS00375	60969..61394	-	426	WP_123035901.1	DUF2384 domain-containing protein	Antitoxin
EDD84_RS00380	61528..61680	-	153	WP_164465441.1	hypothetical protein	-
EDD84_RS00385	62597..63250	+	654	WP_123035903.1	AAA family ATPase	-
EDD84_RS00390	63253..64275	+	1023	WP_098153242.1	ParB/RepB/Spo0J family partition protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..145928	145928

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (11-161)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 19149.81 Da
• Isoelectric Point: 4.8722

>T113695 WP_123035900.1 NZ_CP033429:c60972-60439 [Burkholderia gladioli]
MILTPLQDITAYRMHVPKWAVAPTSGAGAARAGGRANRIGTPALYLALEVATAVAEYQQLSPLLPPGTLVSYRVQATPVV
DFTGGFRADLWPPLWESFFCDWRRDWFNARIEPPSWVLGDEAIAAGAKGILFRSTQAAGGTNLVLFVDQLAEGDRLDVND
PACALPRNQVSWGEPTA

Nucleotide

• Length: 534 bp

>T113695 NZ_CP033429:c60972-60439 [Burkholderia gladioli]
ATGATCCTCACGCCGCTGCAGGACATCACGGCCTATCGCATGCACGTGCCTAAGTGGGCTGTGGCGCCCACCAGTGGCGC
TGGCGCGGCCCGGGCCGGCGGCCGGGCGAACCGGATCGGCACGCCGGCGCTGTATCTGGCGCTCGAGGTGGCCACCGCCG
TGGCCGAGTATCAGCAGCTGTCGCCCCTGCTGCCGCCCGGCACGCTGGTGAGCTATCGGGTCCAGGCGACGCCCGTGGTC
GATTTCACCGGCGGTTTTCGCGCGGATCTCTGGCCACCTCTGTGGGAATCCTTCTTCTGCGACTGGCGCCGCGACTGGTT
CAACGCGCGGATCGAGCCGCCCAGCTGGGTGCTGGGCGACGAGGCGATCGCCGCCGGCGCCAAGGGCATCCTGTTTCGCT
CGACGCAGGCTGCGGGCGGCACGAACCTGGTGCTGTTCGTGGACCAGCTGGCGGAGGGCGATCGCCTGGACGTGAACGAC
CCGGCCTGTGCTCTGCCACGCAACCAGGTCTCCTGGGGCGAGCCGACCGCCTGA

Antitoxin

Protein

• Length: 142 a.a.
• Molecular weight: 15065.94 Da
• Isoelectric Point: 5.7034

>AT113695 WP_123035901.1 NZ_CP033429:c61394-60969 [Burkholderia gladioli]
MSTLAPAREPAAPACGPAPASFDAFLSALREPDTTAPVLSARRYVAALNIDLQTLADQAHVHRNTVARAPQSASVQQFLR
EAIRVIRAATDLSGDVQRALFWYRNEPLAVFDYQTAETLVSAGRADDVVRYVASLEAGAAG

Nucleotide

• Length: 426 bp

>AT113695 NZ_CP033429:c61394-60969 [Burkholderia gladioli]
ATGAGCACCCTCGCACCAGCCCGAGAACCCGCCGCGCCAGCCTGCGGCCCGGCCCCGGCAAGCTTTGATGCATTCCTGAG
TGCGTTGCGCGAGCCGGACACGACGGCTCCCGTGCTGTCGGCCAGGCGTTACGTGGCGGCCCTGAACATCGACTTGCAGA
CGCTCGCCGACCAGGCTCACGTCCACCGAAACACCGTCGCCCGCGCGCCGCAGTCGGCAAGCGTCCAGCAGTTCCTGCGC
GAGGCGATCCGCGTGATCCGCGCCGCGACGGATCTGTCGGGCGACGTCCAGCGCGCGCTGTTCTGGTATCGCAACGAGCC
GCTTGCCGTGTTTGACTACCAGACCGCCGAAACCCTGGTGTCGGCCGGCCGCGCCGATGACGTGGTGCGCTATGTGGCGT
CGCTCGAGGCGGGCGCCGCCGGATGA