Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2041926..2042071 Replicon chromosome
Accession NZ_CP033405
Organism Klebsiella pneumoniae strain WCHKP115069

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2041962..2042064 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2041926..2042071 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DVJ73_RS12745 2037056..2039116 + 2061 WP_004151449.1 oligopeptidase B -
DVJ73_RS12750 2039120..2039779 - 660 WP_002911407.1 exodeoxyribonuclease X -
DVJ73_RS12755 2039858..2040088 - 231 WP_002911406.1 DNA polymerase III subunit theta -
DVJ73_RS12760 2040201..2040575 + 375 WP_004151448.1 CopC domain-containing protein YobA -
DVJ73_RS12765 2040579..2041448 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
DVJ73_RS12770 2041465..2041803 + 339 WP_002911404.1 YebY family protein -
- 2041926..2042071 - 146 - - Antitoxin
- 2041962..2042064 + 103 - - Toxin
DVJ73_RS30295 2042439..2042582 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
DVJ73_RS12780 2042687..2043655 - 969 WP_004151446.1 VirK/YbjX family protein -
DVJ73_RS12785 2043812..2044465 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
DVJ73_RS12790 2044462..2044653 - 192 WP_002911395.1 YebW family protein -
DVJ73_RS12795 2044751..2044990 - 240 WP_002911393.1 YebV family protein -
DVJ73_RS12800 2045106..2046539 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T113672 NZ_CP033405:2041962-2042064 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT113672 NZ_CP033405:c2042071-2041926 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References