Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 1460340..1461259 Replicon chromosome
Accession NZ_CP033389
Organism Bacillus paralicheniformis strain CBMAI 1303

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag D5285_RS07520 Protein ID WP_020451047.1
Coordinates 1460513..1461259 (-) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag D5285_RS07515 Protein ID WP_020451046.1
Coordinates 1460340..1460513 (-) Length 58 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5285_RS07495 1455759..1456856 + 1098 WP_020451042.1 mannonate dehydratase -
D5285_RS07500 1456832..1457680 + 849 WP_020451043.1 SDR family oxidoreductase -
D5285_RS07505 1457708..1458721 + 1014 WP_020451044.1 zinc-binding alcohol dehydrogenase family protein -
D5285_RS07510 1458773..1460044 + 1272 WP_122934918.1 MFS transporter -
D5285_RS07515 1460340..1460513 - 174 WP_020451046.1 type II toxin-antitoxin system SpoIISB family antitoxin Antitoxin
D5285_RS07520 1460513..1461259 - 747 WP_020451047.1 type II toxin-antitoxin system SpoIISA family toxin Toxin
D5285_RS07525 1461369..1462367 - 999 WP_020451048.1 inorganic phosphate transporter -
D5285_RS07530 1462380..1462997 - 618 WP_020451049.1 DUF47 domain-containing protein -
D5285_RS07535 1463329..1465086 + 1758 WP_020451051.1 gamma-glutamyltransferase -
D5285_RS07540 1465223..1465867 + 645 WP_020451052.1 YesL family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-238)

Antitoxin

(1-57)


Sequences


Toxin        


Download         Length: 249 a.a.        Molecular weight: 29435.89 Da        Isoelectric Point: 4.6065

>T113606 WP_020451047.1 NZ_CP033389:c1461259-1460513 [Bacillus paralicheniformis]
MLLFYQFLVWLIVLALALYVAAVWRFEKKLTEKTVAIRKTWYLLYVIGAVIYWTHDPQSIFTNPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSSELATDTRMLLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGNIEAYAEGIEKLIKRFAEKMNISAAL
CEYNSEESKDHLLEHMENRFDVQEKLERKDVYYEENGKMVLIPFSIHDFDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PNEEEGDD

Download         Length: 747 bp

>T113606 NZ_CP033389:c1461259-1460513 [Bacillus paralicheniformis]
ATGCTGCTATTTTATCAATTCCTTGTTTGGCTCATTGTTTTGGCGCTGGCTCTGTATGTAGCTGCCGTGTGGCGTTTTGA
AAAAAAGCTCACCGAAAAAACGGTCGCGATCCGAAAAACGTGGTACCTGCTTTATGTTATCGGCGCCGTGATTTATTGGA
CGCACGATCCGCAGTCGATTTTCACAAACCCGCTTCATTACTTGATCGTTGCCGTTTTTTTCACGCTGACAGACGCTTTT
ATTTTCTTAAACGCCTACTTTAAAAAGCTCGGCAGCTCCGAACTCGCGACAGACACAAGAATGCTTCTCGAAGAAAACAA
CGACCTCCTCCACACATATCAAAACAGGCTGAAAACGTTTCAATACCTATTGAAAAACGAACCGATCCACATCTATTATG
GAAATATAGAAGCGTATGCAGAAGGGATCGAAAAGCTCATCAAACGGTTTGCCGAAAAAATGAATATATCCGCTGCACTT
TGCGAATATAATTCAGAAGAAAGCAAGGATCATTTGCTTGAGCATATGGAAAACCGGTTCGATGTTCAAGAAAAGCTTGA
GCGCAAAGACGTTTATTATGAAGAAAACGGAAAAATGGTCCTCATTCCTTTTTCCATCCACGATTTTGACTATGTCATGA
AGTTAACCTCAGAAGACCTTGTCACAGAATTTGACTACCTCCTGTTTACTTCTTTAACAAGCATCTATGATCTTCTGCTA
CCAAACGAAGAGGAAGGTGACGACTGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6926.00 Da        Isoelectric Point: 10.9186

>AT113606 WP_020451046.1 NZ_CP033389:c1460513-1460340 [Bacillus paralicheniformis]
MEPAFQQDHESAKKRLAFKMFKRQSKTNIAKYEVSPHTERIFRQNERLIGEYKRKKA

Download         Length: 174 bp

>AT113606 NZ_CP033389:c1460513-1460340 [Bacillus paralicheniformis]
ATGGAGCCTGCTTTTCAGCAAGACCATGAAAGCGCAAAAAAGCGCCTCGCCTTTAAAATGTTTAAAAGGCAATCCAAAAC
CAATATCGCGAAATACGAAGTCAGCCCCCATACCGAACGGATTTTCCGGCAAAACGAACGGCTGATCGGCGAGTATAAAA
GAAAAAAAGCTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References