Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 26148..26791 Replicon plasmid pCFSA300-2
Accession NZ_CP033383
Organism Salmonella enterica subsp. enterica strain CFSA300

Toxin (Protein)


Gene name vagD Uniprot ID B1LRW4
Locus tag ECB86_RS01250 Protein ID WP_001044768.1
Coordinates 26148..26564 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID D2WFK3
Locus tag ECB86_RS01255 Protein ID WP_001261287.1
Coordinates 26561..26791 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ECB86_RS01235 22647..23237 - 591 WP_000194575.1 hypothetical protein -
ECB86_RS01240 23237..23494 - 258 WP_000343085.1 hypothetical protein -
ECB86_RS01245 23848..25986 + 2139 WP_000350638.1 AAA family ATPase -
ECB86_RS01250 26148..26564 - 417 WP_001044768.1 type II toxin-antitoxin system VapC family toxin Toxin
ECB86_RS01255 26561..26791 - 231 WP_001261287.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ECB86_RS01260 27087..27377 + 291 WP_000111771.1 hypothetical protein -
ECB86_RS01265 27367..28266 + 900 WP_000963206.1 nucleotide-binding protein -
ECB86_RS01270 28316..30541 - 2226 WP_000698737.1 phage T7 exclusion protein -
ECB86_RS01275 30543..31631 - 1089 WP_000952217.1 transcriptional repressor PifC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..34764 34764


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-137)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 20475.56 Da        Isoelectric Point: 5.5500

>T113601 WP_001044768.1 NZ_CP033383:c26564-26148 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 417 bp

>T113601 NZ_CP033383:c26564-26148 [Salmonella enterica subsp. enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 11350.61 Da        Isoelectric Point: 5.5500

>AT113601 WP_001261287.1 NZ_CP033383:c26791-26561 [Salmonella enterica subsp. enterica]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 231 bp

>AT113601 NZ_CP033383:c26791-26561 [Salmonella enterica subsp. enterica]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A606Q844

Antitoxin

Source ID Structure
AlphaFold DB A0A7U9QFC4

References