Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 759371..760167 Replicon chromosome
Accession NZ_CP033381
Organism Methylomonas sp. LW13

Toxin (Protein)


Gene name ataT Uniprot ID -
Locus tag JL719_RS03330 Protein ID WP_033155977.1
Coordinates 759655..760167 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag JL719_RS03325 Protein ID WP_129871338.1
Coordinates 759371..759658 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JL719_RS03310 754838..756601 + 1764 WP_033155974.1 DUF4942 domain-containing protein -
JL719_RS03315 756734..758329 + 1596 WP_033155975.1 sensor histidine kinase -
JL719_RS03320 758604..759077 + 474 WP_033155976.1 DNA repair protein RadC -
JL719_RS03325 759371..759658 + 288 WP_129871338.1 DUF1778 domain-containing protein Antitoxin
JL719_RS03330 759655..760167 + 513 WP_033155977.1 GNAT family N-acetyltransferase Toxin
JL719_RS03335 761767..761913 + 147 WP_165385915.1 hypothetical protein -
JL719_RS03340 763647..765026 + 1380 WP_201799012.1 radical SAM protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 625288..760499 135211


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(47-147)

Antitoxin

Vibrio phage ICP1, Orf50

(1-95)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18671.69 Da        Isoelectric Point: 7.8237

>T113587 WP_033155977.1 NZ_CP033381:759655-760167 [Methylomonas sp. LW13]
MTALEMSPPGPITTDHRLVDFDCGDTSLNDWLKKRALKNHRAGASRCFVLSVGMDVVAYYCLSAGAISHEASPKTMRRNM
PNPLPVLLLGRLAVDKRYHNQGIGKSLLRDAMLRAVNVSGDAGVFAILVHALSEQAKQFYLSQGFVESPLQAMTLMMTLE
TVREILAEPD

Download         Length: 513 bp

>T113587 NZ_CP033381:759655-760167 [Methylomonas sp. LW13]
ATGACTGCTCTAGAAATGTCGCCCCCAGGACCGATCACGACAGATCATCGGTTGGTGGATTTCGATTGCGGTGATACGTC
GCTGAATGATTGGCTCAAAAAACGTGCACTCAAAAACCATAGGGCAGGGGCTTCGCGTTGTTTTGTACTGAGTGTTGGCA
TGGATGTTGTTGCTTACTACTGCCTGTCTGCCGGTGCAATAAGCCATGAGGCTTCACCCAAAACCATGCGACGCAACATG
CCTAATCCTTTGCCGGTCTTGCTGCTCGGTCGACTGGCTGTCGACAAGCGTTATCATAACCAAGGGATTGGCAAATCGCT
GTTGCGCGATGCAATGCTAAGGGCAGTCAATGTCTCTGGTGATGCGGGAGTATTTGCTATATTGGTTCATGCTCTGTCCG
AACAAGCCAAACAATTTTATCTTTCACAGGGATTTGTGGAGTCACCTTTGCAAGCTATGACTTTGATGATGACGTTAGAG
ACGGTTCGGGAAATTTTGGCTGAACCTGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10843.51 Da        Isoelectric Point: 9.2478

>AT113587 WP_129871338.1 NZ_CP033381:759371-759658 [Methylomonas sp. LW13]
MKQMQTREATPVSINIRAKVRQRDIIDQAAERLGRSRSDFMLEAACRAAEDVLLDQAFFAVDEGAFAQFQALLDQPLPPT
DKLRRLLKTKAPWEK

Download         Length: 288 bp

>AT113587 NZ_CP033381:759371-759658 [Methylomonas sp. LW13]
ATGAAGCAAATGCAAACTAGAGAAGCGACTCCCGTTTCCATTAATATCCGCGCTAAGGTCAGGCAGCGGGATATCATTGA
TCAAGCTGCTGAACGTCTCGGCCGTAGTCGATCAGACTTTATGTTGGAAGCCGCCTGTCGCGCGGCAGAAGATGTGCTTC
TAGATCAGGCATTTTTCGCAGTCGATGAAGGCGCATTTGCACAATTTCAAGCGTTGCTCGATCAACCCTTGCCACCGACT
GATAAGCTTCGCCGGTTACTTAAGACAAAAGCGCCTTGGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References