Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079819..2080090 Replicon chromosome
Accession NZ_CP033378
Organism Escherichia coli strain L73

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079949..2080052 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079819..2080090 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EB670_RS10210 2076374..2077036 - 663 WP_000944258.1 exodeoxyribonuclease X -
EB670_RS10215 2077060..2077716 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EB670_RS10220 2077818..2078048 - 231 WP_000916763.1 DNA polymerase III subunit theta -
EB670_RS10225 2078187..2078561 + 375 WP_000168747.1 CopC domain-containing protein YobA -
EB670_RS10230 2078565..2079437 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EB670_RS10235 2079450..2079791 + 342 WP_000976472.1 YebY family protein -
- 2079819..2080090 - 272 - - Antitoxin
- 2079949..2080052 + 104 - - Toxin
EB670_RS10240 2080187..2080843 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
EB670_RS10245 2080844..2081035 - 192 WP_001338167.1 YebW family protein -
EB670_RS10250 2081140..2081376 - 237 WP_001338166.1 DUF1480 family protein -
EB670_RS10255 2081494..2082933 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T113567 NZ_CP033378:2079949-2080052 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT113567 NZ_CP033378:c2080090-2079819 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References