Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | tacT-ataR/DUF1778(antitoxin) |
Location | 3648205..3648971 | Replicon | chromosome |
Accession | NZ_CP033368 | ||
Organism | Mesorhizobium loti strain SU343 |
Toxin (Protein)
Gene name | tacT | Uniprot ID | A0A6M7TS52 |
Locus tag | EFV37_RS18005 | Protein ID | WP_064984294.1 |
Coordinates | 3648486..3648971 (+) | Length | 162 a.a. |
Antitoxin (Protein)
Gene name | ataR | Uniprot ID | A0A6M7TJG1 |
Locus tag | EFV37_RS18000 | Protein ID | WP_064983733.1 |
Coordinates | 3648205..3648486 (+) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
EFV37_RS17975 | 3643558..3644538 | + | 981 | WP_064983728.1 | ABC transporter permease | - |
EFV37_RS17980 | 3644535..3645521 | + | 987 | WP_019859204.1 | ABC transporter permease | - |
EFV37_RS17985 | 3645638..3646186 | + | 549 | WP_064983730.1 | gluconokinase | - |
EFV37_RS17990 | 3646273..3646722 | - | 450 | WP_019859201.1 | Rrf2 family transcriptional regulator | - |
EFV37_RS17995 | 3646972..3647958 | - | 987 | WP_064983732.1 | sulfate ABC transporter substrate-binding protein | - |
EFV37_RS18000 | 3648205..3648486 | + | 282 | WP_064983733.1 | DUF1778 domain-containing protein | Antitoxin |
EFV37_RS18005 | 3648486..3648971 | + | 486 | WP_064984294.1 | GNAT family N-acetyltransferase | Toxin |
EFV37_RS18010 | 3649024..3650064 | - | 1041 | WP_064983735.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
EFV37_RS18015 | 3650134..3651018 | - | 885 | WP_019859196.1 | sulfate ABC transporter permease subunit CysW | - |
EFV37_RS18020 | 3651011..3651862 | - | 852 | WP_019859195.1 | sulfate ABC transporter permease subunit CysT | - |
EFV37_RS18025 | 3651947..3652975 | - | 1029 | WP_019859193.1 | sulfate ABC transporter substrate-binding protein | - |
EFV37_RS18030 | 3653180..3653911 | - | 732 | WP_019859191.1 | M15 family metallopeptidase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 162 a.a. Molecular weight: 17185.84 Da Isoelectric Point: 9.4412
>T113557 WP_064984294.1 NZ_CP033368:3648486-3648971 [Mesorhizobium loti]
MLSAPAPLAENHDLELFQSGTESLDQWLRRRARANQVGGASRTYVVAEGARVVGYYCLSSGGLDLAEAPGPIRRNMPDPI
PMVVLGRLAVDAGWQGKGLGAALLQDAVLRAGHAATILRIRGIFVHAISDEAKAFYEHYGFAASPKHPMTLVLSLKGLVK
A
MLSAPAPLAENHDLELFQSGTESLDQWLRRRARANQVGGASRTYVVAEGARVVGYYCLSSGGLDLAEAPGPIRRNMPDPI
PMVVLGRLAVDAGWQGKGLGAALLQDAVLRAGHAATILRIRGIFVHAISDEAKAFYEHYGFAASPKHPMTLVLSLKGLVK
A
Download Length: 486 bp
>T113557 NZ_CP033368:3648486-3648971 [Mesorhizobium loti]
ATGCTATCGGCGCCGGCGCCCCTGGCCGAAAACCACGATCTCGAACTTTTCCAAAGTGGGACTGAAAGCCTCGACCAATG
GCTGCGCCGTAGGGCGCGGGCCAACCAAGTCGGTGGCGCGTCTCGGACTTATGTGGTGGCGGAAGGCGCTCGGGTTGTCG
GCTATTACTGCCTGTCTTCGGGCGGGCTTGATCTTGCGGAGGCGCCTGGCCCCATCCGTCGCAACATGCCGGATCCCATC
CCAATGGTCGTACTCGGGCGCCTTGCCGTGGACGCAGGCTGGCAAGGCAAGGGGCTGGGTGCCGCGCTACTGCAAGACGC
CGTTCTGCGCGCCGGCCACGCCGCGACGATCCTCAGGATTCGCGGCATTTTCGTTCATGCCATATCGGATGAGGCGAAAG
CCTTCTACGAGCACTACGGCTTCGCGGCTTCTCCGAAGCATCCAATGACCTTGGTGCTATCGTTGAAGGGCCTGGTGAAA
GCTTAG
ATGCTATCGGCGCCGGCGCCCCTGGCCGAAAACCACGATCTCGAACTTTTCCAAAGTGGGACTGAAAGCCTCGACCAATG
GCTGCGCCGTAGGGCGCGGGCCAACCAAGTCGGTGGCGCGTCTCGGACTTATGTGGTGGCGGAAGGCGCTCGGGTTGTCG
GCTATTACTGCCTGTCTTCGGGCGGGCTTGATCTTGCGGAGGCGCCTGGCCCCATCCGTCGCAACATGCCGGATCCCATC
CCAATGGTCGTACTCGGGCGCCTTGCCGTGGACGCAGGCTGGCAAGGCAAGGGGCTGGGTGCCGCGCTACTGCAAGACGC
CGTTCTGCGCGCCGGCCACGCCGCGACGATCCTCAGGATTCGCGGCATTTTCGTTCATGCCATATCGGATGAGGCGAAAG
CCTTCTACGAGCACTACGGCTTCGCGGCTTCTCCGAAGCATCCAATGACCTTGGTGCTATCGTTGAAGGGCCTGGTGAAA
GCTTAG
Antitoxin
Download Length: 94 a.a. Molecular weight: 10709.28 Da Isoelectric Point: 8.5038
>AT113557 WP_064983733.1 NZ_CP033368:3648205-3648486 [Mesorhizobium loti]
MTKAAPENHAKPVNLRIREDMRILIDRAAKIRGKTRSDFMIDAAYRSAEETLLDQTLIKVDPESYRHYLDILDKPPSGEG
FARLMNAPKPWQD
MTKAAPENHAKPVNLRIREDMRILIDRAAKIRGKTRSDFMIDAAYRSAEETLLDQTLIKVDPESYRHYLDILDKPPSGEG
FARLMNAPKPWQD
Download Length: 282 bp
>AT113557 NZ_CP033368:3648205-3648486 [Mesorhizobium loti]
ATGACAAAGGCCGCCCCTGAGAACCACGCCAAGCCTGTCAATCTGCGTATCCGAGAGGACATGCGCATACTAATTGACCG
CGCCGCGAAAATACGCGGGAAAACCCGCTCCGACTTCATGATCGACGCCGCCTACCGTTCGGCTGAGGAGACGCTGCTCG
ACCAGACCCTGATCAAGGTGGATCCGGAGAGTTACCGGCATTATCTCGACATCCTTGACAAACCGCCAAGCGGGGAGGGT
TTTGCGCGCCTTATGAACGCGCCCAAGCCATGGCAGGACTGA
ATGACAAAGGCCGCCCCTGAGAACCACGCCAAGCCTGTCAATCTGCGTATCCGAGAGGACATGCGCATACTAATTGACCG
CGCCGCGAAAATACGCGGGAAAACCCGCTCCGACTTCATGATCGACGCCGCCTACCGTTCGGCTGAGGAGACGCTGCTCG
ACCAGACCCTGATCAAGGTGGATCCGGAGAGTTACCGGCATTATCTCGACATCCTTGACAAACCGCCAAGCGGGGAGGGT
TTTGCGCGCCTTATGAACGCGCCCAAGCCATGGCAGGACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6M7TS52 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6M7TJG1 |