Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2854558..2855092 Replicon chromosome
Accession NZ_CP033362
Organism Mesorhizobium sp. NZP2077

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EB232_RS14065 Protein ID WP_172226186.1
Coordinates 2854793..2855092 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EB232_RS14060 Protein ID WP_172226183.1
Coordinates 2854558..2854803 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EB232_RS14045 2849615..2851561 + 1947 WP_172226174.1 tetratricopeptide repeat protein -
EB232_RS14050 2851659..2852048 + 390 WP_172226177.1 hypothetical protein -
EB232_RS14055 2852452..2854488 + 2037 WP_172226180.1 tetratricopeptide repeat protein -
EB232_RS14060 2854558..2854803 + 246 WP_172226183.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EB232_RS14065 2854793..2855092 + 300 WP_172226186.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EB232_RS14070 2855150..2855878 - 729 WP_172234701.1 amino acid ABC transporter ATP-binding protein -
EB232_RS14075 2855965..2856639 - 675 WP_019859628.1 amino acid ABC transporter permease -
EB232_RS14080 2856636..2857307 - 672 WP_172226189.1 amino acid ABC transporter permease -
EB232_RS14085 2857412..2858200 - 789 WP_172226192.1 ABC transporter substrate-binding protein -
EB232_RS14090 2858305..2859465 - 1161 WP_172226195.1 saccharopine dehydrogenase family protein -
EB232_RS14095 2859462..2859962 - 501 WP_027044322.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-94)

Antitoxin

Antitoxin ParD

(3-81)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11851.54 Da        Isoelectric Point: 7.3994

>T113541 WP_172226186.1 NZ_CP033362:2854793-2855092 [Mesorhizobium sp. NZP2077]
MPGKSRQYRLSPLAEADLEDIWLYTFKQWSLEQADRYHRDLVDVIEALALGVKTGRRVDVREGYFKYPAGQHFIFFRQSE
TTLDVIRILHQRMDIERHL

Download         Length: 300 bp

>T113541 NZ_CP033362:2854793-2855092 [Mesorhizobium sp. NZP2077]
ATGCCAGGTAAGAGCCGCCAATATCGGCTCTCACCCCTGGCGGAAGCTGATCTGGAAGATATCTGGCTCTATACGTTCAA
ACAGTGGTCATTGGAACAAGCGGATCGGTATCATCGCGATTTGGTCGACGTCATCGAAGCCTTGGCCCTCGGCGTCAAAA
CGGGTCGTCGCGTCGATGTGCGCGAAGGGTATTTCAAATACCCAGCCGGCCAGCATTTCATTTTCTTCCGTCAGTCCGAA
ACGACCCTGGATGTCATCCGCATCCTGCATCAACGCATGGACATTGAACGACATCTGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8612.64 Da        Isoelectric Point: 7.3189

>AT113541 WP_172226183.1 NZ_CP033362:2854558-2854803 [Mesorhizobium sp. NZP2077]
VPRNTSVSLGDHFAGFIDTQVQTGRYGSASDVVRAGLRLLEEHEAKVAALQNALIAGEESGTPVAFDSASFLSRMKAKHA
R

Download         Length: 246 bp

>AT113541 NZ_CP033362:2854558-2854803 [Mesorhizobium sp. NZP2077]
GTGCCCCGAAATACCTCGGTCTCCCTTGGCGATCATTTCGCCGGTTTCATCGATACGCAGGTTCAGACGGGCCGTTATGG
CTCGGCAAGTGATGTCGTGCGTGCCGGTCTGCGGTTGCTCGAAGAACACGAAGCCAAAGTCGCGGCCTTGCAGAACGCCC
TCATTGCCGGCGAAGAATCCGGTACACCTGTCGCCTTCGACAGCGCTTCGTTCCTAAGCAGGATGAAGGCCAAGCATGCC
AGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References