113514

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4277285..4277649 Replicon chromosome
Accession NZ_CP033326
Organism Xanthomonas cucurbitae strain ATCC 23378

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag EBN15_RS18610 Protein ID WP_016904515.1
Coordinates 4277285..4277419 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag EBN15_RS18615 Protein ID WP_003486606.1
Coordinates 4277497..4277649 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBN15_RS18590 4272636..4274288 - 1653 WP_167526970.1 M28 family peptidase -
EBN15_RS18595 4274376..4275314 - 939 WP_159407775.1 MBL fold metallo-hydrolase -
EBN15_RS18600 4275398..4276687 - 1290 WP_167526971.1 tryptophan--tRNA ligase -
EBN15_RS18605 4276842..4277051 - 210 WP_104601868.1 CsbD family protein -
EBN15_RS18610 4277285..4277419 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
EBN15_RS18615 4277497..4277649 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
EBN15_RS18620 4277759..4278682 - 924 WP_104602004.1 arginase -
EBN15_RS18625 4279002..4279454 + 453 WP_159407777.1 roadblock/LC7 domain-containing protein -
EBN15_RS18630 4279522..4279881 + 360 WP_104601870.1 hypothetical protein -
EBN15_RS18635 4279976..4280893 + 918 WP_159407778.1 hypothetical protein -
EBN15_RS18640 4280890..4281429 + 540 WP_104601872.1 ATP/GTP-binding protein -
EBN15_RS18645 4281969..4282649 + 681 WP_104601873.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T113514 WP_016904515.1 NZ_CP033326:c4277419-4277285 [Xanthomonas cucurbitae]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T113514 NZ_CP033326:c4277419-4277285 [Xanthomonas cucurbitae]
ATGAAGCGTGCAATCGTGCTGCTGGTGCTGTCAGTGTTGTCGGTCGGGATGCTGTCAGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCCGGCGAGAAGGTGGAAGACGCCGCACGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT113514 WP_003486606.1 NZ_CP033326:c4277649-4277497 [Xanthomonas cucurbitae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT113514 NZ_CP033326:c4277649-4277497 [Xanthomonas cucurbitae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGCGCCGGCAACAAGGTCGAGAAGACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References