113513

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 3611610..3613330 Replicon chromosome
Accession NZ_CP033326
Organism Xanthomonas cucurbitae strain ATCC 23378

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag EBN15_RS15650 Protein ID WP_104602389.1
Coordinates 3611610..3612260 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag EBN15_RS15655 Protein ID WP_159407552.1
Coordinates 3612260..3613330 (+) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EBN15_RS15625 3607527..3608177 + 651 WP_159407550.1 SGNH/GDSL hydrolase family protein -
EBN15_RS15630 3608184..3608585 + 402 WP_159407551.1 hypothetical protein -
EBN15_RS15635 3608726..3609397 + 672 WP_104602386.1 methyltransferase -
EBN15_RS15640 3609597..3610388 - 792 WP_208800396.1 polysaccharide deacetylase family protein -
EBN15_RS15645 3610434..3611360 + 927 WP_104602388.1 Grx4 family monothiol glutaredoxin -
EBN15_RS15650 3611610..3612260 + 651 WP_104602389.1 DUF4433 domain-containing protein Toxin
EBN15_RS15655 3612260..3613330 + 1071 WP_159407552.1 macro domain-containing protein Antitoxin
EBN15_RS15660 3613432..3613992 - 561 WP_104602391.1 DUF924 family protein -
EBN15_RS15665 3614132..3615532 + 1401 WP_159407553.1 amidohydrolase -
EBN15_RS15670 3615529..3616809 + 1281 WP_159407554.1 amidohydrolase family protein -
EBN15_RS15675 3616956..3617771 - 816 Protein_3063 cellulase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3598977..3613330 14353


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 25041.42 Da        Isoelectric Point: 7.2475

>T113513 WP_104602389.1 NZ_CP033326:3611610-3612260 [Xanthomonas cucurbitae]
MSRRYLNLNPDKALIWRIVHRDNLPWILDNGLHCGNGSARSPGWVSIGNPELIDKRACHPVPLTPGGFLNDYVPFYFTPF
SPMLRNIQTGWGGIQQRANDEIVILVSSLHHVKARGWPFLFTDSHAYYQLTTFHSDLTNLDTIDWSLIQARDFRRDQEDP
AKFERYQAEALVHRHLPVDGLLGIVCYTDDMKRSIERQLEARNLALSVHARTEWYF

Download         Length: 651 bp

>T113513 NZ_CP033326:3611610-3612260 [Xanthomonas cucurbitae]
ATGTCTAGGCGCTACCTCAACCTCAATCCAGACAAAGCCCTGATCTGGCGCATCGTCCACCGCGATAATCTGCCTTGGAT
TCTGGACAACGGCCTGCATTGCGGTAACGGCAGCGCGCGTAGTCCGGGCTGGGTAAGCATCGGCAATCCTGAATTGATCG
ACAAGCGCGCCTGTCATCCTGTGCCGCTTACACCCGGCGGCTTCCTGAACGATTACGTGCCCTTCTACTTCACTCCATTT
TCGCCAATGCTTCGCAACATCCAGACCGGCTGGGGAGGCATCCAACAACGCGCTAACGATGAAATTGTGATCCTTGTGTC
CAGCTTGCATCATGTCAAGGCACGTGGGTGGCCCTTCCTGTTCACCGATAGTCATGCCTACTATCAGTTGACAACGTTCC
ATTCCGATTTGACCAATCTGGACACGATCGACTGGTCGCTGATCCAGGCGCGCGATTTTCGCCGCGATCAGGAGGATCCG
GCCAAGTTCGAACGATATCAGGCCGAAGCGCTGGTCCACCGACACCTGCCCGTCGACGGCTTGCTCGGCATCGTGTGTTA
TACGGACGACATGAAGCGTTCCATCGAACGTCAGCTTGAAGCCCGAAACCTTGCACTTTCCGTGCATGCCCGCACCGAGT
GGTACTTCTGA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 39768.68 Da        Isoelectric Point: 6.2605

>AT113513 WP_159407552.1 NZ_CP033326:3612260-3613330 [Xanthomonas cucurbitae]
MITFTQGNLLQARVEALVNTVNTVGVMGKGIALMFKERFNENFLRYAAACKAKEVQIGKMFVTATSELDGPRWIINFPTK
QHWRGDSRIEWITDGLQDLRLFLIENKVESIAIPPLGAGNGGLDWADVRPLIEEALAGLDTNILVFEPTPRYQNVAKRSG
VEKLTPARALIAELVRRYLVLGVECSLLEIQKLAWFLERNIERAGLPTLDLRFAPHRYGPYTDRLRHLLDGLDGSYLHCD
KRIGDADPLDVIWFDDSRKSFVQSYLKSEAKQYAPALEATAALIDGFESPFGMELLATIDWLVVREGISAQVADIREGIR
HWPGGPDAAARKDRLFNDRALGIALERLTSHAAAAS

Download         Length: 1071 bp

>AT113513 NZ_CP033326:3612260-3613330 [Xanthomonas cucurbitae]
ATGATTACGTTTACGCAAGGCAATCTACTGCAGGCGCGCGTCGAGGCGTTGGTCAACACTGTCAACACCGTTGGAGTGAT
GGGTAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAACGAAAACTTCCTCCGATATGCAGCAGCCTGCAAGGCAAAAG
AAGTGCAGATCGGCAAGATGTTCGTCACTGCGACCAGCGAACTGGACGGACCACGCTGGATTATCAATTTCCCGACCAAA
CAGCACTGGCGTGGCGATTCACGAATCGAATGGATTACCGACGGGTTGCAGGATCTGCGCCTGTTCCTGATCGAAAACAA
GGTCGAGTCGATTGCCATCCCGCCGCTGGGCGCCGGCAATGGAGGCTTGGACTGGGCCGACGTGCGCCCACTGATCGAAG
AGGCGCTTGCCGGGCTAGATACCAATATTCTCGTATTCGAACCCACTCCAAGATATCAAAATGTCGCAAAGCGTTCCGGC
GTGGAGAAGCTGACTCCAGCGCGCGCATTGATTGCCGAACTGGTACGTCGCTACTTGGTGCTAGGCGTGGAATGCAGCCT
GTTGGAGATCCAGAAGCTTGCCTGGTTCCTTGAACGCAATATCGAGCGCGCCGGCTTGCCTACGTTGGATTTGCGCTTTG
CGCCACACCGGTACGGGCCATATACCGATCGTCTGCGCCACCTGCTGGATGGGCTGGACGGCAGTTATCTTCACTGTGAC
AAGCGAATCGGAGACGCAGACCCCCTGGATGTCATCTGGTTCGATGATTCTCGCAAAAGCTTTGTGCAGAGCTATCTCAA
GAGCGAAGCCAAGCAGTATGCCCCTGCACTGGAAGCCACTGCAGCCTTGATCGATGGCTTTGAATCTCCTTTTGGCATGG
AGTTGCTGGCAACCATTGACTGGTTGGTCGTACGGGAGGGCATCTCTGCGCAAGTGGCAGATATCCGCGAGGGGATTCGC
CACTGGCCGGGCGGCCCAGATGCAGCCGCGCGCAAAGACAGATTGTTCAACGACCGCGCCTTGGGCATCGCCCTGGAACG
ACTCACATCACATGCGGCTGCAGCGAGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References