Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2139201..2139888 Replicon chromosome
Accession NZ_CP033236
Organism Saccharolobus solfataricus strain SARC-H

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SULH_RS11965 Protein ID WP_231918326.1
Coordinates 2139553..2139888 (+) Length 112 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SULH_RS11960 Protein ID WP_009991659.1
Coordinates 2139201..2139503 (+) Length 101 a.a.

Genomic Context

SULH_RS11945SULH_RS11960SULH_RS11965SULH_RS11970SULH_RS15360SULH_RS12000SULH_RS11940SULH_RS11950SULH_RS11955SULH_RS11975SULH_RS11980SULH_RS11990SULH_RS11995
Location: 2135996..2136663 (668 bp)
Type: Others
Protein ID: Protein_2312
Location: 2139201..2139503 (303 bp)
Type: Antitoxin
Protein ID: WP_009991659.1
Location: 2139553..2139888 (336 bp)
Type: Toxin
Protein ID: WP_231918326.1
Location: 2140096..2141211 (1116 bp)
Type: Others
Protein ID: WP_009991657.1
Location: 2141962..2142153 (192 bp)
Type: Others
Protein ID: WP_048056702.1
Location: 2144150..2144488 (339 bp)
Type: Others
Protein ID: WP_010923427.1
Location: 2135125..2135668 (544 bp)
Type: Others
Protein ID: Protein_2311
Location: 2137072..2137644 (573 bp)
Type: Others
Protein ID: WP_010923431.1
Location: 2137660..2138672 (1013 bp)
Type: Others
Protein ID: Protein_2314
Location: 2141355..2141690 (336 bp)
Type: Others
Protein ID: Protein_2318
Location: 2141872..2142017 (146 bp)
Type: Others
Protein ID: Protein_2319
Location: 2142413..2142910 (498 bp)
Type: Others
Protein ID: WP_014511660.1
Location: 2143052..2144025 (974 bp)
Type: Others
Protein ID: Protein_2322
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SULH_RS11940 (SULH_11950)2135125..2135668-544Protein_2311IS607 family transposase-
SULH_RS11945 (SULH_11955)2135996..2136663+668Protein_2312ISNCY family transposase-
SULH_RS11950 (SULH_11960)2137072..2137644-573WP_010923431.1metallophosphoesterase-
SULH_RS11955 (SULH_11965)2137660..2138672-1013Protein_2314IS630-like element ISC1078 family transposase-
SULH_RS11960 (SULH_11970)2139201..2139503+303WP_009991659.1hypothetical proteinAntitoxin
SULH_RS11965 (SULH_11975)2139553..2139888+336WP_231918326.1type II toxin-antitoxin system VapC family toxinToxin
SULH_RS11970 (SULH_11980)2140096..2141211+1116WP_009991657.1hypothetical protein-
SULH_RS11975 (SULH_11985)2141355..2141690-336Protein_2318transposase-
SULH_RS11980 (SULH_11990)2141872..2142017-146Protein_2319IS630 family transposase-
SULH_RS153602141962..2142153+192WP_048056702.1hypothetical protein-
SULH_RS11990 (SULH_12000)2142413..2142910-498WP_014511660.1hypothetical protein-
SULH_RS11995 (SULH_12005)2143052..2144025-974Protein_2322IS5 family transposase-
SULH_RS12000 (SULH_12010)2144150..2144488+339WP_010923427.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--2098409..2311978213569
-insideIScluster/Tn--2133891..214766713776


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-104)

Antitoxin

Putative antitoxin VapB3-like

(28-100)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12427.61 Da        Isoelectric Point: 5.2389

>T113436 WP_231918326.1 NZ_CP033236:2139553-2139888 [Saccharolobus solfataricus]
IREILKDAETLDFALVEVSNVVWKKAVLTGELTGKDVIKAITIVKEYLPQLLTVNKSIDLIERAIEISVNEKITVYDSLY
IALAECKGSKLVTGDKKQYDVAKKYVISELI

Download         Length: 336 bp

>T113436 NZ_CP033236:2139553-2139888 [Saccharolobus solfataricus]
ATTAGAGAGATTTTGAAAGACGCTGAGACATTAGACTTCGCATTAGTGGAAGTATCTAACGTAGTATGGAAGAAAGCTGT
ATTAACTGGGGAATTAACTGGGAAAGATGTAATTAAGGCAATTACTATTGTTAAAGAGTATTTACCACAACTGCTTACAG
TTAACAAAAGCATTGACTTAATTGAAAGAGCTATTGAGATTTCCGTTAACGAGAAAATCACAGTATATGATTCACTTTAT
ATTGCACTGGCTGAATGTAAGGGGAGTAAATTGGTAACGGGGGATAAGAAACAATACGACGTAGCTAAAAAGTACGTCAT
CTCTGAGCTCATATAG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 12195.09 Da        Isoelectric Point: 4.8275

>AT113436 WP_009991659.1 NZ_CP033236:2139201-2139503 [Saccharolobus solfataricus]
MVIKNATILIYVPEIETFIFPVYVYYNMKTVYSLRLDKELREEMEKYNVKWNEEIESFIRKRIEELKKEEILKKINEILQ
TMPETKSNSADLVREDRDNN

Download         Length: 303 bp

>AT113436 NZ_CP033236:2139201-2139503 [Saccharolobus solfataricus]
ATGGTAATAAAGAATGCTACAATTTTAATCTATGTACCAGAGATAGAAACGTTTATATTTCCCGTATACGTGTATTATAA
TATGAAAACCGTATACAGTTTAAGGTTAGATAAGGAATTACGTGAGGAGATGGAGAAATATAACGTCAAGTGGAATGAGG
AGATAGAGAGCTTTATAAGAAAGAGAATTGAGGAATTGAAGAAAGAGGAGATCTTAAAGAAGATTAATGAAATCCTCCAA
ACAATGCCAGAAACTAAGTCAAATAGTGCAGATTTGGTGAGGGAAGATAGGGATAATAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References